Oro-mucosal administration of oxytocin using medicated lollipops alters social attention, similar to intranasal and lingual routes: Implications for therapeutic use

D Xu, Q Li, Q Zhuang, Y Zhang, S Yao… - Frontiers in …, 2022 - frontiersin.org
A key functional effect of intranasal administration of the neuropeptide oxytocin is on top-
down control of social attention. However, an oro-mucosal administration route may be …

Oral administration of oxytocin, like intranasal administration, decreases top-down social attention

Q Zhuang, X Zheng, S Yao, W Zhao… - International Journal …, 2022 - academic.oup.com
Background The neuropeptide oxytocin (OXT) modulates social cognition by increasing
attention to social cues and may have therapeutic potential for impaired social attention in …

Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

Oxytocin reduces top-down control of attention by increasing bottom-up attention allocation to social but not non-social stimuli–a randomized controlled trial

X Xu, J Li, Z Chen, KM Kendrick, B Becker - Psychoneuroendocrinology, 2019 - Elsevier
The neuropeptide oxytocin (OXT) may facilitate attention to social stimuli by influencing early
stage bottom-up processing although findings in relation to different emotional expressions …

Effects of intranasal administration of oxytocin and vasopressin on social cognition and potential routes and mechanisms of action

S Yao, KM Kendrick - Pharmaceutics, 2022 - mdpi.com
Acute and chronic administration of intranasal oxytocin and vasopressin have been
extensively utilized in both animal models and human preclinical and clinical studies over …

In the nose or on the tongue? Contrasting motivational effects of oral and intranasal oxytocin on arousal and reward during social processing

J Kou, C Lan, Y Zhang, Q Wang, F Zhou, Z Zhao… - Translational …, 2021 - nature.com
Intranasal oxytocin exerts wide-ranging effects on socioemotional behavior and is proposed
as a potential therapeutic intervention in psychiatric disorders. However, following intranasal …

Intranasal oxytocin effects on social cognition: a critique

SL Evans, O Dal Monte, P Noble, BB Averbeck - Brain research, 2014 - Elsevier
The last decade has seen a large number of published findings supporting the hypothesis
that intranasally delivered oxytocin (OT) can enhance the processing of social stimuli and …

Oxytocin effects on the human brain: findings, questions, and future directions

O Weisman, R Feldman - Biological Psychiatry, 2013 - biologicalpsychiatryjournal.com
Since the discovery that intranasal administration of neuro-peptides can have a direct impact
on the human brain, extant research has been devoted to understanding the effects of …

[HTML][HTML] Intranasal oxytocin increases perceptual salience of faces in the absence of awareness

SW Xue, HB Wu, L Zhang, DX Zhang - Psychiatry Investigation, 2020 - ncbi.nlm.nih.gov
Objective The neuropeptide oxytocin has been found to improve human social cognition and
promote prosocial behavior. However, it is still unclear about the mechanisms underlying …

Intranasal oxytocin does not reduce age-related difficulties in social cognition

SA Grainger, JD Henry, HR Steinvik, EJ Vanman… - Hormones and …, 2018 - Elsevier
Oxytocin is a neuropeptide that plays a key role in social processing and there are several
studies suggesting that intranasally administered oxytocin may enhance social cognitive …