Faecal virome transplantation decreases symptoms of type 2 diabetes and obesity in a murine model

TS Rasmussen, CMJ Mentzel, W Kot, JL Castro-Mejía… - Gut, 2020 - gut.bmj.com
Objective Development of obesity and type 2 diabetes (T2D) are associated with gut
microbiota (GM) changes. The gut viral community is predominated by bacteriophages …

[HTML][HTML] Phage-microbe dynamics after sterile faecal filtrate transplantation in individuals with metabolic syndrome: a double-blind, randomised, placebo-controlled …

K Wortelboer, PA de Jonge, TPM Scheithauer… - Nature …, 2023 - nature.com
Bacteriophages (phages) are bacterial viruses that have been shown to shape microbial
communities. Previous studies have shown that faecal virome transplantation can decrease …

Faecal microbiota transplantation‐mediated jejunal microbiota changes halt high‐fat diet‐induced obesity in mice via retarding intestinal fat absorption

L Zhu, J Fu, X Xiao, F Wang, M Jin… - Microbial …, 2022 - Wiley Online Library
Summary Faecal Microbiota Transplantation (FMT) is considered as a promising technology
to fight against obesity. Wild boar has leanermuscle and less fat in comparison to the …

[HTML][HTML] The gut virome: A new microbiome component in health and disease

Z Cao, N Sugimura, E Burgermeister, MP Ebert… - …, 2022 - thelancet.com
The human gastrointestinal tract harbours an abundance of viruses, collectively known as
the gut virome. The gut virome is highly heterogeneous across populations and is linked to …

[HTML][HTML] High fat diet drives obesity regardless the composition of gut microbiota in mice

S Rabot, M Membrez, F Blancher, B Berger, D Moine… - Scientific reports, 2016 - nature.com
The gut microbiota is involved in many aspects of host physiology but its role in body weight
and glucose metabolism remains unclear. Here we studied the compositional changes of …

[HTML][HTML] Focus: microbiome: treating obesity and metabolic syndrome with fecal microbiota transplantation

CA Marotz, A Zarrinpar - The Yale journal of biology and medicine, 2016 - ncbi.nlm.nih.gov
The worldwide prevalence of metabolic syndrome, which includes obesity and its associated
diseases, is rising rapidly. The human gut microbiome is recognized as an independent …

Roles of the gut virome and mycobiome in faecal microbiota transplantation

S Lam, X Bai, AN Shkoporov, H Park, X Wu… - The Lancet …, 2022 - thelancet.com
Faecal microbiota transplantation (FMT) is an innovative approach to treat diseases that are
associated with gut dysbiosis, by transferring a healthy stool microbiota to a recipient with …

[HTML][HTML] The gut virome is associated with stress-induced changes in behaviour and immune responses in mice

NL Ritz, LA Draper, TFS Bastiaanssen… - Nature …, 2024 - nature.com
The microbiota–gut–brain axis has been shown to play an important role in the stress
response, but previous work has focused primarily on the role of the bacteriome. The gut …

Donor metabolic characteristics drive effects of faecal microbiota transplantation on recipient insulin sensitivity, energy expenditure and intestinal transit time

P de Groot, T Scheithauer, GJ Bakker, A Prodan… - Gut, 2020 - gut.bmj.com
Objective Bariatric surgery improves glucose metabolism. Recent data suggest that faecal
microbiota transplantation (FMT) using faeces from postbariatric surgery diet-induced obese …

[HTML][HTML] Fecal microbiota transplantation confers beneficial metabolic effects of diet and exercise on diet-induced obese mice

ZL Lai, CH Tseng, HJ Ho, CKY Cheung, JY Lin… - Scientific reports, 2018 - nature.com
Diet and exercise are conventional methods for controlling body weight and are linked to
alterations in gut microbiota. However, the associations of diet, exercise, and gut microbiota …