Communication among cells via direct cell-cell contact by connexin gap junctions, or
between cell and extracellular environment via pannexin channels or connexin …

Since their characterization more than five decades ago, gap junctions and their structural
proteins—the connexins—have been associated with cancer cell growth. During that period …

Cellular communication through gap junctions and hemichannels formed by connexins and
through channels made by pannexins allows for metabolic cooperation and control of …

Connexins and pannexins are two families of large-pore channel forming proteins that are
capable of passing small signaling molecules. While connexins serve the seminal task of …

It is nowadays well established that gap junctions are critical gatekeepers of cell
proliferation, by controlling the intercellular exchange of essential growth regulators. In …

Connexins (Cxs), the gap junction proteins, have been found to be downregulated in many
types of cancers including gliomas. By restoring gap junctional communication in cancer cell …

Gap junctions (GJs) are composed of proteins that form a channel connecting the cytoplasm
of adjacent cells. Connexins were initially considered to be the only proteins capable of GJ …

Mammalian gap junction proteins, connexins, have long been implicated in tumor
suppression. Recently, a novel family of proteins named pannexins has been identified as …

Connexins had been considered to be the only class of the vertebrate proteins capable of
gap junction formation; however, new candidates for this function with no homology to …

Regulation of bone homeostasis depends on the concerted actions of bone-forming
osteoblasts and bone-resorbing osteoclasts, controlled by osteocytes, cells derived from …