This article is a review of the genes and genetic disorders that affect hearing in humans and
a few selected mouse models of deafness. Genetics is playing an increasingly critical role in …

Hearing loss (HL), or deafness in its most severe form, affects an estimated 28 and 22.5
million Americans and Europeans, respectively. The numbers are higher in regions such as …

Hearing loss is among the most common disabilities of man. It has been estimated that over
70 million individuals in the world are hearing impaired with pure tone averages greater …

The genetic heterogeneity of hereditary hearing loss is thus far represented by hundreds of
genes encoding a large variety of proteins. Mutations in these genes have been discovered …

Remarkable progress has been made over the past few years in the field of hereditary
deafness. To date, mutations in at least 35 genes are known to cause hearing loss. We are …

Perception of sound is a fundamental role of the auditory system. Traveling with the force of
their mechanical energy, sound waves are captured by the ear and activate the sensory …

What would define real progress in the field of deafness research in fundamental and
medical terms? In fundamental terms, progress would be measured by an improvement in …

Research in the genetics of hearing and deafness has evolved rapidly over the past years,
providing the molecular foundation for different aspects of the mechanism of hearing …

Congenital hearing impairment affects nearly 1 in every 1000 live births and is the most
frequent birth defect in developed societies. Hereditary types of hearing loss account for …

The study of hereditary hearing impairments provides a unique opportunity to deal with two
objectives simultaneously:(i) identification of the causative genes and the underlying …