The cytochromes P450 constitute a large family of cysteinato-heme enzymes, 1-9 are
present in all forms of life (plants, bacteria, and mammals), and play a key role in the …

Cytochrome P450 enzymes catalyze a broad diversity of reactions, including well-
established transformations such as carbon and nitrogen hydroxylation, heteroatom …

The reactions catalyzed by the cytochrome P450 family of enzymes have challenged and
intrigued chemists for more than two decades. Alkane hydroxylation and olefin epoxidation …

The significance of cytochrome P450 catalyzed reactions has now been recognized for more
than 30 years [1] as one of nature's most common and sophisticated methods to oxidize …

Cytochrome P‐450 (P‐450) enzymes catalyze the oxidation of a wide variety of substrates.
Although a large number of P‐450s have been characterized in different species and …

This review discusses the mechanisms of oxygen activation by cytochrome P450 enzymes,
the possible catalytic roles of the various iron—oxygen species formed in the catalytic cycle …

Cytochromes P-450 are ubiquitous in nature. The levels of these hemoproteins can be
influenced by many chemicals and the enzymes in turn are capable of me-tabolizing many …

Cytochrome P-450 enzymes (EC 1.14. 14.1, nonspecific monooxygenase) catalyze the
oxidations of many chemicals (1). The mass of the substrates ranges from that of ethylene …

The three editions of Cytochrome P450: Structure, Mechanism, and Biochemistry have
appeared at approximately tenyear intervals and present a snapshot of the field of …

Cytochrome P450 enzymes (P450s) comprise a large class of enzymes that effect numerous
oxidations in nature. The active oxidants in P450s are thought to be iron (IV)− oxo porphyrin …