Tumor-associated calcium signal transducer 2 regulates neovascularization of non-small-cell lung cancer via activating ERK1/2 signaling pathway
X Guo, X Zhu, L Zhao, X Li, D Cheng… - Tumor Biology, 2017 - journals.sagepub.com
Lung cancer, especially the non-small-cell lung cancer, is a highly aggressive vascular
cancer with excessively activated signaling pathways. Tumor-associated calcium signal …
cancer with excessively activated signaling pathways. Tumor-associated calcium signal …
TROP2 overexpression promotes proliferation and invasion of lung adenocarcinoma cells
Z Li, X Jiang, W Zhang - Biochemical and biophysical research …, 2016 - Elsevier
Recent studies suggest that the human trophoblast cell-surface antigen TROP2 is highly
expressed in a number of tumours and is correlated with poor prognosis. However, its role in …
expressed in a number of tumours and is correlated with poor prognosis. However, its role in …
Trop2 enhances invasion of thyroid cancer by inducing MMP2 through ERK and JNK pathways
H Guan, Z Guo, W Liang, H Li, G Wei, L Xu, H Xiao, Y Li - Bmc Cancer, 2017 - Springer
Background Mounting evidence has showed that Tumor-associated calcium signal
transducer 2 (Trop2) is upregulated in various kinds of human cancers and plays important …
transducer 2 (Trop2) is upregulated in various kinds of human cancers and plays important …
TROP2 increases growth and metastasis of human oral squamous cell carcinoma through activation of the PI3K/Akt signaling pathway
G Tang, Q Tang, L Jia, Y Chen… - International …, 2019 - spandidos-publications.com
Most malignant neoplasms of the oral cavity are oral squamous cell carcinoma (OSCC),
which is a type of highly malignant tumor with a propensity for forming distant metastases …
which is a type of highly malignant tumor with a propensity for forming distant metastases …
Upregulation of Trop-2 quantitatively stimulates human cancer growth
M Trerotola, P Cantanelli, E Guerra, R Tripaldi… - Oncogene, 2013 - nature.com
Trop-2 is a calcium signal transducer that is associated with transformed cell growth in
experimental systems. However, its role in human cancer remains essentially unknown. In …
experimental systems. However, its role in human cancer remains essentially unknown. In …
Tumor Endothelial Marker 8 Promotes Proliferation and Metastasis via the Wnt/β-Catenin Signaling Pathway in Lung Adenocarcinoma
C Ding, J Liu, J Zhang, Y Wan, L Hu… - Frontiers in …, 2021 - frontiersin.org
Tumor endothelial marker 8 (TEM8), also known as ANTXR1, was highly expressed in
cancers, and was identified as a biomarker for early diagnosis and prognosis in some …
cancers, and was identified as a biomarker for early diagnosis and prognosis in some …
TNF-α promotes colon cancer cell migration and invasion by upregulating TROP-2
P Zhao, Z Zhang - Oncology letters, 2018 - spandidos-publications.com
High levels of tumor-associated calcium signal transduction protein (TROP)‑2 have been
demonstrated to be strongly associated with tumor necrosis factor (TNF)‑α levels in colon …
demonstrated to be strongly associated with tumor necrosis factor (TNF)‑α levels in colon …
Clinical impact of TROP2 in non‐small lung cancers and its correlation with abnormal p53 nuclear accumulation
R Mito, E Matsubara, Y Komohara… - Pathology …, 2020 - Wiley Online Library
Tumor‐associated calcium signal transducer 2 (TROP2) is a cell‐surface glycoprotein
involved in the high malignant potential of several cancers. Antibody‐drug conjugates that …
involved in the high malignant potential of several cancers. Antibody‐drug conjugates that …
[HTML][HTML] TROP2 modulates the progression in papillary thyroid carcinoma
H Sun, Q Chen, W Liu, Y Liu, S Ruan, C Zhu… - Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Tumor-associated calcium signal transducer 2 (TROP2) is over expressed in
various kinds of human cancers and plays important roles in the proliferation, invasion and …
various kinds of human cancers and plays important roles in the proliferation, invasion and …
Targeting ONECUT2 inhibits tumor angiogenesis via down-regulating ZKSCAN3/VEGFA
L Zhang, C Li, X Song, R Guo, W Zhao, C Liu… - Biochemical …, 2024 - Elsevier
OC-2 plays a vital role in tumor growth, metastasis and angiogenesis, but molecular
mechanism how OC-2 regulates angiogenic factors is unclear. We found that OC-2 was …
mechanism how OC-2 regulates angiogenic factors is unclear. We found that OC-2 was …