Phytoestrogen supplements for the treatment of hot flashes: the Isoflavone Clover Extract (ICE) Study: a randomized controlled trial

JA Tice, B Ettinger, K Ensrud, R Wallace, T Blackwell… - Jama, 2003 - jamanetwork.com
ContextClinical trials demonstrating increased risk of cardiovascular disease and breast
cancer among women randomized to hormone replacement therapy have increased interest …

Isoflavone supplements containing predominantly genistein reduce hot flash symptoms: a critical review of published studies

PS Williamson-Hughes, BD Flickinger, MJ Messina… - Menopause, 2006 - journals.lww.com
Objective: Several reviews have evaluated the clinical evidence relating isoflavone
treatment to the relief of menopausal hot flash symptoms. The majority of these reviews …

Extracted or synthesized soybean isoflavones reduce menopausal hot flash frequency and severity: systematic review and meta-analysis of randomized controlled …

K Taku, MK Melby, F Kronenberg, MS Kurzer… - Menopause, 2012 - journals.lww.com
Objective This analysis was conducted to determine the efficacy of extracted or synthesized
soybean isoflavones in the alleviation of hot flashes in perimenopausal and …

Nonhormonal therapies for menopausal hot flashes: systematic review and meta-analysis

HD Nelson, KK Vesco, E Haney, R Fu, A Nedrow… - Jama, 2006 - jamanetwork.com
ContextConcern regarding the adverse effects of estrogen and other hormones for treating
menopausal symptoms has led to demand for other options; however, the efficacy and …

Effects of isoflavones and amino acid therapies for hot flashes and co-occurring symptoms during the menopausal transition and early postmenopause: a systematic …

AJ Thomas, R Ismail, L Taylor-Swanson, L Cray… - Maturitas, 2014 - Elsevier
Aims Review controlled clinical trials of isoflavones and amino acid preparation effects on
hot flashes and at least one other symptom including mood, sleep, pain, and cognitive …

Quantitative efficacy of soy isoflavones on menopausal hot flashes

L Li, Y Lv, L Xu, Q Zheng - British journal of clinical …, 2015 - Wiley Online Library
Aim This study aimed to quantitate the efficacy of soy isoflavones in the treatment of
menopausal hot flashes. Methods Model based meta‐analysis (MBMA) was used to …

Randomized placebo-controlled trial of an isoflavone supplement and menopausal symptoms in women

RJ Baber, C Templeman, T Morton, GE Kelly, L West - Climacteric, 1999 - Taylor & Francis
Objective To test the hypothesis that increasing the intake of isoflavones by dietary
supplementation may produce a therapeutic effect in reducing the incidence and severity of …

Isoflavones from red clover (Promensil®) significantly reduce menopausal hot flush symptoms compared with placebo

PHM van de Weijer, R Barentsen - Maturitas, 2002 - Elsevier
Objectives: To investigate the effectiveness and safety of a red clover isoflavone dietary
supplement (Promensil, Novogen Ltd., Australia) versus placebo on the change in hot flush …

Soy extract phytoestrogens with high dose of isoflavones for menopausal symptoms

A Ferrari - Journal of Obstetrics and Gynaecology Research, 2009 - Wiley Online Library
Aim: The aim of the present study was to assess the efficacy and safety of a standardized
compound based on an extract of soy phytoestrogens, with high doses of isoflavones in the …

Efficacy of soyfoods and soybean isoflavone supplements for alleviating menopausal symptoms is positively related to initial hot flush frequency

M Messina, C Hughes - Journal of Medicinal Food, 2003 - liebertpub.com
Soy has received attention as an alternative to conventional hormone replacement therapy
(HRT) largely because it is a unique dietary source of isoflavones. Isoflavones are …