Slow waves promote sleep-dependent plasticity and functional recovery after stroke

L Facchin, C Schöne, A Mensen… - Journal of …, 2020 - Soc Neuroscience
Functional recovery after stroke is associated with a remapping of neural circuits. This
reorganization is often associated with low-frequency, high-amplitude oscillations in the peri …

[HTML][HTML] Sleep as a model to understand neuroplasticity and recovery after stroke: observational, perturbational and interventional approaches

A Mensen, A Pigorini, L Facchin, C Schöne… - Journal of neuroscience …, 2019 - Elsevier
Our own experiences with disturbances to sleep demonstrate its crucial role in the recovery
of cognitive functions. This importance is likely enhanced in the recovery from stroke; both in …

Recovery of consolidation after sleep following stroke—interaction of slow waves, spindles, and GABA

J Kim, L Guo, A Hishinuma, S Lemke, DS Ramanathan… - Cell reports, 2022 - cell.com
Sleep is known to promote recovery after stroke. Yet it remains unclear how stroke affects
neural processing during sleep. Using an experimental stroke model in rats along with …

[HTML][HTML] The role of sleep in recovery following ischemic stroke: a review of human and animal data

SB Duss, A Seiler, MH Schmidt, M Pace… - Neurobiology of sleep …, 2017 - Elsevier
Despite advancements in understanding the pathophysiology of stroke and the state of the
art in acute management of afflicted patients as well as in subsequent neurorehabilitation …

Brain-wide neural dynamics of poststroke recovery induced by optogenetic stimulation

S Vahdat, AV Pendharkar, T Chiang, S Harvey… - Science …, 2021 - science.org
Poststroke optogenetic stimulations can promote functional recovery. However, the circuit
mechanisms underlying recovery remain unclear. Elucidating key neural circuits involved in …

Essential thalamic contribution to slow waves of natural sleep

F David, JT Schmiedt, HL Taylor, G Orban… - Journal of …, 2013 - Soc Neuroscience
Slow waves represent one of the prominent EEG signatures of non-rapid eye movement
(non-REM) sleep and are thought to play an important role in the cellular and network …

Optogenetic approaches to study stroke recovery

MY Cheng, EH Wang, GK Steinberg - ACS chemical neuroscience, 2014 - ACS Publications
Treatment for stroke is very limited, and potential new therapies are focusing on promoting
brain repair and plasticity, as they offer a longer therapeutic time window than the current US …

Why does sleep slow-wave activity increase after extended wake? Assessing the effects of increased cortical firing during wake and sleep

AV Rodriguez, CM Funk, VV Vyazovskiy… - Journal of …, 2016 - Soc Neuroscience
During non-rapid eye movement (NREM) sleep, cortical neurons alternate between ON
periods of firing and OFF periods of silence. This bi-stability, which is largely synchronous …

Local sleep oscillations: implications for memory consolidation

M Geva-Sagiv, Y Nir - Frontiers in neuroscience, 2019 - frontiersin.org
Accumulating evidence suggests that sleep is important for plasticity and memory
consolidation (Maquet, 2001; Walker and Stickgold, 2004; Datta and Maclean, 2007; …

[HTML][HTML] EEG slow waves in traumatic brain injury: Convergent findings in mouse and man

MH Modarres, NN Kuzma, T Kretzmer, AI Pack… - Neurobiology of sleep …, 2017 - Elsevier
Objective Evidence from previous studies suggests that greater sleep pressure, in the form
of EEG-based slow waves, accumulates in specific brain regions that are more active during …