The relationship between egg polarity and the adult body plan is well understood in many
bilaterians. However, the evolutionary origins of embryonic polarity are not known. Insight …

Cnidarians are fascinating creatures at the base of metazoan evolution possessing an
almost unlimited regeneration capacity that has attracted the interest of researchers, from …

The primary axis of cnidarians runs from the oral pole to the apical tuft and defines the major
body axis of both the planula larva and adult polyp. In the anthozoan cnidarian Nematostella …

Due to their rather simple body plan with only few organs and a low number of cell types,
cnidarians have long been recognized as an important animal group for evolutionary …

Cnidarians (corals, sea anemones, hydroids, and jellyfish) are a basal taxon closely related
to bilaterally symmetrical animals [1–3] and have been characterized as diploblastic and as …

The development of the oral pole in cnidarians and the posterior pole in bilaterians is
regulated by canonical Wnt signaling, whereas a set of transcription factors, including Six3/6 …

Among the basally branching metazoans, cnidarians display well-defined gastrulation
processes leading to a diploblastic body plan, consisting of an endodermal and an …

The conserved family of Wnt signaling molecules mediates various developmental
processes including governing cell fate, proliferation, and polarity. The diverse …

The origin of the bilaterian head is a fundamental question for the evolution of animal body
plans. The head of bilaterians develops at the anterior end of their primary body axis and is …

Cnidarians, in contrast with bilaterians, are generally considered to exhibit radial symmetry
around a single body axis (oral–aboral) throughout their life-cycles. We have investigated …