BRCA mutation carriers' perception about benefits and risks associated with combined hormonal contraceptives use

G Grandi, F Monari, V Boggio Sola… - … European Journal of …, 2022 - Taylor & Francis
Objective To evaluate the actual perceptions about combined hormonal contraceptives
(CHCs) use in BRCA mutation carriers in comparison to women from the general population …

[HTML][HTML] Combined hormonal contraceptives in BRCA gene mutation carriers: why not?

G Grandi, M Sammarini… - … European Journal of …, 2019 - Taylor & Francis
Germline mutations in BRCA1 and BRCA2 account for a large proportion of hereditary
breast and ovarian cancers. These tumour suppressor genes, respectively, located in …

[HTML][HTML] Contraception and hormone replacement therapy in healthy carriers of germline BRCA1/2 genes pathogenic variants: results from an Italian survey

C Massarotti, B Buonomo, M Dellino, M Campanella… - Cancers, 2022 - mdpi.com
Simple Summary Being a healthy carrier of a BRCA1/2 pathogenetic variant is not a
contraindication to hormonal contraception and menopause hormonal therapy; however …

Contraceptives and cancer risks in BRCA1/2 pathogenic variant carriers: a systematic review and meta-analysis

MHD van Bommel, J IntHout, G Veldmate… - Human …, 2023 - academic.oup.com
BACKGROUND Increasing numbers of BReast CAncer (BRCA) 1 or 2 pathogenic variant
(PV) carriers, who have an inherited predisposition to breast and ovarian cancer, are being …

[HTML][HTML] Long term use of oral contraceptives comprising synthetic estrogens induces an excessive breast cancer risk in BRCA mutation carrier women: A meta …

H Peng, X Qi, Q Wang - Clinical and Experimental Obstetrics & …, 2022 - imrpress.com
Background: The relationship between oral contraceptive (OC) use and breast cancer risk is
highly debated. Recent publications support a slight increase in overall breast cancer risk …

[HTML][HTML] Use of oral contraceptives in BRCA mutation carriers and risk for ovarian and breast cancer: a systematic review

D Huber, S Seitz, K Kast, G Emons… - Archives of gynecology and …, 2020 - Springer
Purpose BRCA mutation carriers have an increased risk of developing breast or ovarian
cancer. Oral contraception (OC) is known to increase breast cancer and reduce ovarian …

Contraceptive use and the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation

YY Xia, J Gronwald, B Karlan, J Lubinski… - Gynecologic …, 2022 - Elsevier
Abstract Background BRCA1 and BRCA2 (BRCA) mutation carriers face a high lifetime risk
of developing ovarian cancer. Oral contraceptives are protective in this population; however …

Changes in health-related behaviours following BRCA1/2 genetic testing: the case of hormone replacement therapy

I Rouleau, J Chiquette, M Plante, J Simard… - Journal of Obstetrics and …, 2004 - Elsevier
Objective: To determine hormone replacement therapy (HRT) use among women at high
risk for breast cancer and ovarian cancer, before genetic testing for the cancer susceptibility …

BRCA mutation carriers' perceptions on postmenopausal hormone therapy: An Italian study

G Grandi, V Boggio Sola, L Cortesi, A Toss… - Psycho …, 2021 - Wiley Online Library
Objective To evaluate the actual perceptions of postmenopausal hormone therapy (HT) in
BRCA mutation carriers (BRCAmc) in comparison with women from the general population …

Oral contraceptives and risk of ovarian and breast cancers in BRCA mutation carriers: a meta-analysis

D Cibula, M Zikan, L Dusek, O Majek - Expert review of anticancer …, 2011 - Taylor & Francis
Prophylactic salpingo-oophorectomy is currently the only effective strategy available for
decreasing ovarian cancer risk in BRCA1/2 mutation carriers. Significantly decreased risk of …