[HTML][HTML] Design and synthesis of new N-thioacylated ciprofloxacin derivatives as urease inhibitors with potential antibacterial activity
A new series of N-thioacylated ciprofloxacin 3a–n were designed and synthesized based on
Willgerodt–Kindler reaction. The results of in vitro urease inhibitory assay indicated that …
Willgerodt–Kindler reaction. The results of in vitro urease inhibitory assay indicated that …
Design, synthesis, molecular docking, anti-Proteus mirabilis and urease inhibition of new fluoroquinolone carboxylic acid derivatives
MAA Abdullah, GEDAA Abuo-Rahma… - Bioorganic …, 2017 - Elsevier
New hydroxamic acid, hydrazide and amide derivatives of ciprofloxacin in addition to their
analogues of levofloxacin were prepared and identified by different spectroscopic …
analogues of levofloxacin were prepared and identified by different spectroscopic …
Different barbiturate derivatives linked to aryl hydrazone moieties as urease inhibitors; design, synthesis, urease inhibitory evaluations, and molecular dynamic …
New series of barbiturates linked to aryl hydrazone derivatives 4a-n were designed and
synthesized. Briefly, aniline derivatives in the presence of HBF4 and NaNO2 convert to aryl …
synthesized. Briefly, aniline derivatives in the presence of HBF4 and NaNO2 convert to aryl …
Identification and molecular modeling of new quinolin-2-one thiosemicarbazide scaffold with antimicrobial urease inhibitory activity
MAI Elbastawesy, YAMM El-Shaier, M Ramadan… - Molecular Diversity, 2021 - Springer
A new series of 6-substituted quinolin-2-one thiosemicarbazides 6a–j has been synthesized.
The structure of the target compounds was proved by different spectroscopic and elemental …
The structure of the target compounds was proved by different spectroscopic and elemental …
[HTML][HTML] New thioxothiazolidinyl-acetamides derivatives as potent urease inhibitors: Design, synthesis, in vitro inhibition, and molecular dynamic simulation
N Dastyafteh, M Noori, M Nazari Montazer… - Scientific Reports, 2023 - nature.com
To identify potent urease inhibitors, in the current study, a series of thioxothiazolidinyl-
acetamides were designed and synthesized. The prepared compounds were characterized …
acetamides were designed and synthesized. The prepared compounds were characterized …
Antibacterial and urease inhibitory activity of new piperazinyl N-4 functionalized ciprofloxacin-oxadiazoles
M AA Abdel-Aal, SA Abdel-Aziz… - Journal of Modern …, 2019 - jmr.journals.ekb.eg
This research includes design of new ciprofloxacin bearing oxadiazole at the N-4
piperazinyl for the purpose of having urease inhibitory activity as well as antibacterial …
piperazinyl for the purpose of having urease inhibitory activity as well as antibacterial …
[PDF][PDF] Fluoroquinolones as urease inhibitors: anti-Proteus mirabilis activity and molecular docking studies
The anti-Proteus mirabilis activity and MIC of levofloxacin and ciprofloxacin were
investigated in comparison with the known urease inhibitor acetohydroxamic acid using Well …
investigated in comparison with the known urease inhibitor acetohydroxamic acid using Well …
A novel, rapid and eco-sustainable approach for the synthesis of novel benzothiazole derivatives as potent urease inhibitors: biological assay, molecular docking …
Recently, benzothiazole derivatives have garnered significant attention among the research
community due to their pharmaceutical and biological significance. Likewise, in this study …
community due to their pharmaceutical and biological significance. Likewise, in this study …
[HTML][HTML] Arylmethylene hydrazine derivatives containing 1, 3-dimethylbarbituric moiety as novel urease inhibitors
A new series of arylmethylene hydrazine derivatives bearing 1, 3-dimethylbarbituric moiety
7a–o were designed, synthesized, and evaluated for their in vitro urease inhibitory activity …
7a–o were designed, synthesized, and evaluated for their in vitro urease inhibitory activity …
[HTML][HTML] Design and synthesis of novel nitrothiazolacetamide conjugated to different thioquinazolinone derivatives as anti-urease agents
The present article describes the design, synthesis, in vitro urease inhibition, and in silico
molecular docking studies of a novel series of nitrothiazolacetamide conjugated to different …
molecular docking studies of a novel series of nitrothiazolacetamide conjugated to different …