[HTML][HTML] Variable effects of acoustic trauma on behavioral and neural correlates of tinnitus in individual animals

RJ Longenecker, AV Galazyuk - Frontiers in behavioral neuroscience, 2016 - frontiersin.org
The etiology of tinnitus is known to be diverse in the human population. An appropriate
animal model of tinnitus should incorporate this pathological diversity. Previous studies …

[HTML][HTML] Alterations in peripheral and central components of the auditory brainstem response: a neural assay of tinnitus

AS Lowe, JP Walton - PLoS One, 2015 - journals.plos.org
Chronic tinnitus, or “ringing of the ears”, affects upwards of 15% of the adult population.
Identifying a cost-effective and objective measure of tinnitus is needed due to legal concerns …

Neural changes accompanying tinnitus following unilateral acoustic trauma in the guinea pig

B Coomber, JI Berger, VL Kowalkowski… - European Journal of …, 2014 - Wiley Online Library
Animal models of tinnitus allow us to study the relationship between changes in neural
activity and the tinnitus percept. Here, guinea pigs were subjected to unilateral noise trauma …

[HTML][HTML] Changes in the response properties of inferior colliculus neurons relating to tinnitus

JI Berger, B Coomber, TT Wells, MN Wallace… - Frontiers in …, 2014 - frontiersin.org
Tinnitus is often identified in animal models by using the gap prepulse inhibition of acoustic
startle. Impaired gap detection following acoustic over-exposure (AOE) is thought to be …

[HTML][HTML] Development of tinnitus in CBA/CaJ mice following sound exposure

RJ Longenecker, AV Galazyuk - Journal of the Association for Research in …, 2011 - Springer
Tinnitus, the perception of a sound without an external acoustic source, is a complex
perceptual phenomenon affecting the quality of life in 17% of the adult population. Despite …

[HTML][HTML] A conditioned behavioral paradigm for assessing onset and lasting tinnitus in rats

E Pace, H Luo, M Bobian, A Panekkad, X Zhang… - PLoS …, 2016 - journals.plos.org
Numerous behavioral paradigms have been developed to assess tinnitus-like behavior in
animals. Nevertheless, they are often limited by prolonged training requirements, as well as …

[HTML][HTML] Gap-induced reductions of evoked potentials in the auditory cortex: A possible objective marker for the presence of tinnitus in animals

JI Berger, W Owen, CA Wilson, A Hockley, B Coomber… - Brain Research, 2018 - Elsevier
Animal models of tinnitus are essential for determining the underlying mechanisms and
testing pharmacotherapies. However, there is doubt over the validity of current behavioural …

[HTML][HTML] Comparison of two behavioral tests for tinnitus assessment in mice

EM Fabrizio-Stover, G Nichols, J Corcoran… - Frontiers in behavioral …, 2022 - frontiersin.org
Animal research focused on chronic tinnitus associated with noise-induced hearing loss can
be expensive and time-consuming as a result of the behavioral training required. Although …

Psychophysical and neural correlates of noised-induced tinnitus in animals: Intra-and inter-auditory and non-auditory brain structure studies

J Zhang, H Luo, E Pace, L Li, B Liu - Hearing research, 2016 - Elsevier
Tinnitus, a ringing in the ear or head without an external sound source, is a prevalent health
problem. It is often associated with a number of limbic-associated disorders such as anxiety …

Behavioral evidence for possible simultaneous induction of hyperacusis and tinnitus following intense sound exposure

G Chen, C Lee, SA Sandridge, HM Butler… - Journal of the …, 2013 - Springer
Many human subjects suffering from chronic tinnitus also suffer from hyperacusis, a
heightened perception of loudness at moderate to intense sound levels. While numerous …