[HTML][HTML] Methylated DNA/RNA in body fluids as biomarkers for lung cancer

Y Lu, SSL Li, SSG Zhu, YYB Gong, JJ Shi… - Biological Procedures …, 2017 - Springer
DNA/RNA methylation plays an important role in lung cancer initiation and progression.
Liquid biopsy makes use of cells, nucleotides and proteins released from tumor cells into …

Applying circulating tumor DNA methylation in the diagnosis of lung cancer

L Li, K Fu, W Zhou, M Snyder - Precision Clinical Medicine, 2019 - academic.oup.com
Lung cancer is the leading cause of cancer-related deaths worldwide. Low dose computed
tomography (LDCT) is commonly used for disease screening, with identified candidate …

[HTML][HTML] Methylation analyses in liquid biopsy

D Lissa, AI Robles - Translational lung cancer research, 2016 - ncbi.nlm.nih.gov
Lung cancer is the leading cause of cancer-related deaths worldwide. Recent
implementation of low-dose computed tomography (LDCT) screening is predicted to lead to …

[HTML][HTML] Cell Free Methylated Tumor DNA in Bronchial Lavage as an Additional Tool for Diagnosing Lung Cancer—A Systematic Review

SWC Wen, J Wen, TF Hansen, A Jakobsen, O Hilberg - Cancers, 2022 - mdpi.com
Simple Summary Lung cancer causes the highest number of cancer-related deaths. The
prognosis is poor, primarily because the disease is often diagnosed at an advanced stage …

DNA methylation analysis of selected genes for the detection of early-stage lung cancer using circulating cell-free DNA.

Z Yang, W Qi, L Sun, H Zhou… - Advances in Clinical & …, 2019 - search.ebscohost.com
Background. Lung cancer is still the deadliest cancer in the world, but early diagnosis
cannot be achieved because of the limitations of diagnostic methods. DNA methylation has …

[HTML][HTML] Non-invasive diagnosis of early-stage lung cancer using high-throughput targeted DNA methylation sequencing of circulating tumor DNA (ctDNA)

W Liang, Y Zhao, W Huang, Y Gao, W Xu, J Tao… - Theranostics, 2019 - ncbi.nlm.nih.gov
Rational: LDCT screening can identify early-stage lung cancers yet introduces excessive
false positives and it remains a great challenge to differentiate malignant tumors from benign …

[HTML][HTML] DNA methylation in lung cancer patients: Opening a" window of life" under precision medicine

R Liang, X Li, W Li, X Zhu, C Li - Biomedicine & Pharmacotherapy, 2021 - Elsevier
DNA methylation is a work of adding a methyl group to the 5th carbon atom of cytosine in
DNA sequence under the catalysis of DNA methyltransferase (DNMT) to produce 5-methyl …

DNA methylation biomarkers discovered in silico detect cancer in liquid biopsies from non-small cell lung cancer patients

L Vrba, MM Oshiro, SS Kim, LL Garland, C Placencia… - Epigenetics, 2020 - Taylor & Francis
Identification of cancer-specific methylation of DNA released by tumours can be used for non-
invasive diagnostics and monitoring. We previously reported in silico identification of DNA …

[HTML][HTML] DNA methylation-based biomarkers for early detection of non-small cell lung cancer: an update

PP Anglim, TA Alonzo, IA Laird-Offringa - Molecular cancer, 2008 - Springer
Lung cancer is the number one cancer killer in the United States. This disease is clinically
divided into two sub-types, small cell lung cancer,(10–15% of lung cancer cases), and non …

[HTML][HTML] Circulating tumor DNA methylation biomarkers for characterization and determination of the cancer origin in malignant liver tumors

T Draškovič, N Zidar, N Hauptman - Cancers, 2023 - mdpi.com
Simple Summary Malignant liver tumors consist of primary tumors and metastases. A correct
diagnosis can be achieved with different methods; one of them is the analysis of the cell-free …