The lipid raft hypothesis proposed that these microdomains are small (10–200 nM), highly
dynamic and enriched in cholesterol, glycosphingolipids and signalling phospholipids …

Lipid rafts, solid regions of the plasma membrane enriched in cholesterol and
glycosphingolipids, are essential parts of a cell. Functionally, lipid rafts present a platform …

Accumulating reports document the use by pathogens of cholesterol‐enriched lipid
microdomains, often called lipid rafts, as cell surface platforms to interact, bind and possibly …

Microbial pathogenesis: Lipid rafts as pathogen portals: Current Biology Skip to Main Content
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Infectious diseases pose major socioeconomic and health-related threats to millions of
people across the globe. Strategies to combat infectious diseases derive from our …

Numerous pathogens have evolved mechanisms of co-opting normal host endocytic
machinery as a means of invading host cells. While numerous pathogens have been known …

Pathogenic bacteria have developed various mechanisms to evade host immune defense
systems. Invasion of pathogenic bacteria requires interaction of the pathogen with host …

Lipid rafts are defined as detergent-resistant membrane microdomains of specific lipid and
protein composition. They are involved in many aspects of cell biology, including T-cell …

Lipid rafts are defined as specialized, dynamic microdomains that can be found in plasma
membrane, and they are enriched with cholesterol and sphingolipids. Since lipid rafts' first …

Throughout evolution, organisms have developed immune-surveillance networks to protect
themselves from potential pathogens. At the cellular level, the signalling events that regulate …