Cellular metabolism is a key regulator of energetics, cell growth, regeneration, and
homeostasis. Spatially mapping the heterogeneity of cellular metabolic activity is of great …

Only 30% of embryos from in vitro fertilized oocytes successfully implant and develop to
term, leading to repeated transfer cycles. To reduce time-to-pregnancy and stress for …

Hyperspectral imaging is highly sought after in many fields including mineralogy and
geology, environment and agriculture, astronomy and, importantly, biomedical imaging and …

Abstract Development of quantitative, safe and rapid techniques for assessing embryo
quality provides significant advances in Assisted Reproductive Technologies (ART). Instead …

Several techniques rely on detection of fluorescence signals to identify or study phenomena
or to elucidate functions. Separation of these fluorescence signals were proven …

Rather than simply acting as a photographic camera capturing two‐dimensional (x, y)
intensity images or a spectrometer acquiring spectra (λ), a hyperspectral imager measures …

Current approaches for assessing embryo quality are subjective (morphology) or invasive
(biopsy) and are not always predictive of live birth. Development of an accurate and non …

By the 1950s, optical microscopy in the life sciences had fallen out of favor. The improved
electron microscope offered higher resolving power that facilitated the study of new cell …

Optical microscopic imaging offers opportunities to perform noninvasive assessments of
numerous parameters associated with the biochemistry, morphology, and functional state of …

Two-photon imaging of endogenous fluorescence can provide physiological and metabolic
information from intact tissues. However, simultaneous imaging of multiple intrinsic …