Context High levels of lipoprotein (a) are associated with increased risk of myocardial
infarction (MI). Objective To assess whether genetic data are consistent with this association …

Background Genetically elevated plasma lipoprotein (a) and familial hypercholesterolemia
each result in premature atherosclerotic cardiovascular disease (ASCVD); however, a direct …

Background Lipoprotein (a) is an atherogenic low-density lipoprotein–like particle and
circulating levels are largely determined by genetics. Patients with familial …

Background: Genomic analyses have suggested that the LPA gene and its associated
plasma biomarker, lipoprotein (a)(Lp [a]), represent a causal risk factor for coronary heart …

The aim of this review is to summarize present evidence of a causal association of
lipoprotein (a) with risk of ischemic heart disease (IHD). Evidence for causality includes …

This study reviews ancestral differences in the genetics of the LPA gene, risk categories of
elevated lipoprotein (a)[Lp (a)] as defined by guidelines, ancestry-specific Lp (a) risk …

Aims With the current focus on lipoprotein (a) as a likely causal risk factor for cardiovascular
disease and new drugs potentially on the market to lower lipoprotein (a) levels, the safety of …

Objectives: This study sough to test whether elevated lipoprotein (a) levels and
corresponding LPA risk genotypes (low number of kringle IV type 2 repeats, rs3798220 and …

Importance Human genetic studies have indicated that plasma lipoprotein (a)(Lp [a]) is
causally associated with the risk of coronary heart disease (CHD), but randomized trials of …

Background Lipoprotein (a) concentrations in plasma are associated with cardiovascular
risk in the general population. Whether lipoprotein (a) concentrations or LPA genetic …