Due to their unique properties, such as programmability, ligand-binding capability, and
flexibility, nucleic acids can serve as analytes and/or recognition elements for biosensing. To …

Detection of low-abundance nucleic acids is a challenging task, which over the last two
decades has been solved using enzymatic target amplification. Enzymatic synthesis …

Nucleic acids have been actively applied to various sensing tools and future biodevices
because of their high biocompatibility, as well as their programmable properties and …

Nucleic acid fluorescent probes are playing increasingly important roles in biological
sensing in recent years. In addition to the conventional functions of single-stranded …

Detection of a single biomolecule, ranging from nucleic acids, proteins, viruses to bacteria, is
of paramount importance in various fields including biology, environment, food and …

Nucleic acid amplification techniques are broadly employed in nucleic acid testing due to
their efficient accumulation of nucleic acid sequences. With the development of …

Integrating nucleic acid circuits (NACs) with functional DNA probes has emerged as a
promising platform in the field of biosensing, offering a facile and versatile way of detecting a …

Single-molecule fluorescence imaging is among the most advanced analytical technologies
and has been widely adopted for biosensing due to its distinct advantages of simplicity …

Enzyme-free, signal-amplified nucleic acid circuits utilize programmed assembly reactions
between nucleic acid substrates to transduce a chemical input into an amplified detection …

Nucleic acid biosensors, integrated with functional nucleic acids, have drawn extensive
attention for diverse biomedical applications. In particular, many nucleic acid probes have …