Microtubule organization, dynamics and functions in differentiated cells

A Muroyama, T Lechler - Development, 2017 - journals.biologists.com
Over the past several decades, numerous studies have greatly expanded our knowledge
about how microtubule organization and dynamics are controlled in cultured cells in vitro …

Mechanisms of microtubule organization in differentiated animal cells

A Akhmanova, LC Kapitein - Nature Reviews Molecular Cell Biology, 2022 - nature.com
Microtubules are polarized cytoskeletal filaments that serve as tracks for intracellular
transport and form a scaffold that positions organelles and other cellular components and …

Microtubules: Evolving roles and critical cellular interactions

CM Logan, AS Menko - Experimental Biology and Medicine, 2019 - journals.sagepub.com
Microtubules are cytoskeletal elements known as drivers of directed cell migration, vesicle
and organelle trafficking, and mitosis. In this review, we discuss new research in the lens …

From signaling pathways to microtubule dynamics: the key players

S Etienne-Manneville - Current opinion in cell biology, 2010 - Elsevier
Microtubules are highly dynamic structures whose regulation is crucial for cell division, cell
polarity, cell migration, or neuronal differentiation. Because they contribute to most cellular …

Interplay between microtubule dynamics and intracellular organization

H de Forges, A Bouissou, F Perez - … journal of biochemistry & cell biology, 2012 - Elsevier
Microtubules are hollow tubes essential for many cellular functions such as cell polarization
and migration, intracellular trafficking and cell division. They are polarized polymers …

Microtubule assembly, organization and dynamics in axons and dendrites

C Conde, A Cáceres - Nature Reviews Neuroscience, 2009 - nature.com
During the past decade enormous advances have been made in our understanding of the
basic molecular machinery that is involved in the development of neuronal polarity. Far from …

ReMAPping the microtubule landscape: How phosphorylation dictates the activities of microtubule‐associated proteins

A Ramkumar, BY Jong… - Developmental …, 2018 - Wiley Online Library
Classical microtubule‐associated proteins (MAPs) were originally identified based on their
co‐purification with microtubules assembled from mammalian brain lysate. They have since …

Microtubule organization in vitro

M Dogterom, T Surrey - Current opinion in cell biology, 2013 - Elsevier
Microtubules organize into a set of distinct patterns with the help of associated molecules
that control nucleation, polymerization, crosslinking, and transport. These patterns, alone or …

Microtubule-organizing centers

J Wu, A Akhmanova - Annual review of cell and developmental …, 2017 - annualreviews.org
The organization of microtubule networks is crucial for controlling chromosome segregation
during cell division, for positioning and transport of different organelles, and for cell polarity …

[HTML][HTML] Evolutionary conservation of microtubule-capture mechanisms

GG Gundersen - Nature Reviews Molecular Cell Biology, 2002 - nature.com
The dynamic nature of microtubules allows them to search the three-dimensional space of
the cell. But what are they looking for? During cellular morphogenesis, microtubules are …