Doxorubicin (otherwise known as Adriamycin) is one of the antibiotic cytotoxic agent
belonging to the anthracycline class of anticancer agents [1]. Doxorubicin is known to bind to …

Cardiotoxicity as an off‐target effect of doxorubicin therapy is a major limiting factor for its
clinical use as a choice cytotoxic agent. Seeds of Irvingia gabonensis have been reported to …

Doxorubicin (DOX), with an anthracyclic structure, routinely used intravenously for
newlinethe treatment of various types of cancers. However, the incidence of renal failure …

Background: Worldwide, the major death causing diseases are cardiovascular diseases and
today the need for herb based therapeutics is needed. Present study was undertaken the …

Context: Ficus racemosa Linn.(Moraceae) bark is a rich source of phenolic compounds
having diverse biological properties including antioxidant activity. The present study …

One of the most efficient anthracycline anti-cancer medications, doxorubicin, is used to treat
lymphoid malignancies. Intercalation with deoxyribonucleic acid is a key component of its …

Doxorubicin (DOX) is a widely used anthracycline antibiotic for the management of
carcinoma. However, it is associated with cardiotoxicity. Fisetin is a plant flavonoid reported …

Cardiotoxicity is defined as drug-induced damage to the heart muscle, which can result in
cardiac failure or cardiac arrest. Cardiotoxicity is a common side effect of traditional …

Introduction: Severe cardiotoxicity limits the use of doxorubicin in cancer treatment.
Doxorubicin toxicity involves the generation of reactive oxygen species (ROS) and hence …

Background: Doxorubicin as an anti-cancer drug causes cardiotoxicity, limiting its tolerability
and use. The mechanism of toxicity is due to free radical production and cardiomyocytes …