Motile and non-motile (primary) cilia are nearly ubiquitous cellular organelles. The
dysfunction of cilia causes diseases known as ciliopathies. The number of reported …

Once obscure, the cilium has come into the spotlight during the past decade. It is now clear
that aside from generating locomotion by motile cilia, both motile and immotile cilia serve as …

Ciliopathies are inherited human disorders caused by both motile and non‐motile cilia
dysfunction that form an important and rapidly expanding disease category. Ciliopathies are …

Primary cilia have a broad tissue distribution and are present on most cell types in the
human body. Until recently, they were considered to be redundant organelles, but progress …

Recent studies of the primary cilium have begun to provide further insights into ciliary
ultrastructure, with an emerging picture of complex compartmentalization and molecular …

Ciliopathies comprise a group of complex disorders, with involvement of the majority of
organs and systems. In total,> 180 causal genes have been identified and, in addition to …

Genetic diseases known as ciliopathies have recently entered the limelight, placing new
importance on a previously mysterious organelle: the primary cilium. Mutations affecting the …

Motile cilia have long been known to play a role in processes such as cell locomotion and
fluid movement whereas the functions of primary cilia have remained obscure until recent …

Over the last 5 years, disorders of nonmotile cilia have come of age and their study has
contributed immeasurably to our understanding of cell biology and human genetics. This …

Cilia are conserved, microtubule-based cell surface projections that emanate from basal
bodies, membrane-docked centrioles. The beating of motile cilia and flagella enables cells …