[HTML][HTML] Urothelial carcinoma management in elderly or unfit patients

J Bellmunt, N Mottet, M De Santis - European Journal of Cancer …, 2016 - Elsevier
Strategies to improve cancer care in the field of urothelial carcinoma (UC) in the elderly or in
patients unfit to receive cisplatin treatment are urgently needed. This effort requires …

[HTML][HTML] The outcome of elderly patients with advanced urothelial carcinoma after platinum-based combination chemotherapy

A Bamias, E Efstathiou, LA Moulopoulos, D Gika… - Annals of oncology, 2005 - Elsevier
Background The majority of patients with advanced urothelial cancer are elderly, but data
regarding this specific age group are limited. We compared the tolerability and efficacy of …

Management of elderly patients with urothelial carcinoma of the bladder: guideline concordance and predictors of overall survival

C Bolenz, R Ho, GR Nuss, N Ortiz, GV Raj… - BJU …, 2010 - Wiley Online Library
Study Type–Therapy (case series) Level of Evidence 4 OBJECTIVE To study guideline
recommendation (GR)‐concordance rates of treatment in elderly patients with urothelial …

The evolving treatment landscape of advanced urothelial carcinoma

AY Andreev-Drakhlin, G Egoryan… - Current opinion in …, 2021 - journals.lww.com
The evolving treatment landscape of advanced urothelial carc... : Current Opinion in Oncology
The evolving treatment landscape of advanced urothelial carcinoma : Current Opinion in …

New emerging targets in advanced urothelial carcinoma: Is it the primetime for personalized medicine?

M Audisio, M Tucci, RF Di Stefano, E Parlagreco… - Critical Reviews in …, 2022 - Elsevier
In recent years the introduction of immunotherapy has importantly changed the treatment
landscape of advanced urothelial carcinoma. Several immune checkpoint inhibitors are now …

Neoadjuvant chemotherapy in elderly patients with bladder cancer: oncologic outcomes from a single institution experience

AR Leone, K Zargar-Shoshtari, GJ Diorio… - Clinical genitourinary …, 2017 - Elsevier
Introduction We conducted this study to determine if, in appropriately selected elderly
patients receiving neoadjuvant chemotherapy (NAC), clinical outcomes including pathologic …

Management of advanced urothelial carcinoma in older and frail patients: have novel treatment approaches improved their care?

BM Russell, L Boussi, J Bellmunt - Drugs & Aging, 2022 - Springer
Patients with urothelial carcinoma tend to be older and frailer with a large number of chronic
medical conditions. This is particularly pronounced in those with unresectable locally …

[HTML][HTML] Clinical evidence for the first-line treatment of advanced urothelial carcinoma: Current paradigms and emerging treatment options

M Koufopoulou, PAP Miranda, P Kazmierska… - Cancer treatment …, 2020 - Elsevier
Background Patients with advanced urothelial carcinoma (UC) have poor outcomes, with 5-
year survival rates of< 5% for those with metastatic, stage IV disease. We have reviewed …

Bladder cancer

DJ Gallagher, MI Milowsky - Current treatment options in oncology, 2009 - Springer
Opinion statement Bladder cancer is a complex disease of older patients with coexisting
medical problems requiring multimodal therapy. For patients with localized bladder cancer …

[HTML][HTML] Real-world treatment patterns and clinical outcomes among patients with advanced urothelial carcinoma in the United States

DM Geynisman, E Broughton, Y Hao, Y Zhang… - … Oncology: Seminars and …, 2022 - Elsevier
Introduction This large-scale, US-based study characterized real-world treatment patterns
and clinical outcomes in patients with advanced or metastatic urothelial carcinoma (aUC) …