Withaferin A targets the membrane of Pseudomonas aeruginosa and mitigates the inflammation in zebrafish larvae; an in vitro and in vivo approach

R Murugan, R Rajesh, B Seenivasan… - Microbial …, 2022 - Elsevier
Infections due to multidrug-resistant Pseudomonas aeruginosa are prevalent among
patients with cystic fibrosis. The emergence of antibiotic-resistant pathogens necessitated …

Bacterial clearance and anti-inflammatory effect of Withaferin A against human pathogen of Staphylococcus aureus in infected zebrafish

R Murugan, S Subramaniyan, S Priya… - Aquatic Toxicology, 2023 - Elsevier
The emergence of antibiotic resistance is the most challenging factor for developing a
proper drug to treat S. aureus infection. These bacterial pathogens can survive in fresh water …

[HTML][HTML] Treatment with paeoniflorin increases lifespan of Pseudomonas aeruginosa infected Caenorhabditis elegans by inhibiting bacterial accumulation in …

Y Wang, L Zhang, X Yuan, D Wang - Frontiers in Pharmacology, 2023 - frontiersin.org
Paeoniflorin is one of the important components in Paeoniaceae plants. In this study, we
used Caenorhabditis elegans as a model host and Pseudomonas aeruginosa as a bacterial …

Alleviation effect of Deinococcus sp. Y35 together with autoinducer 2 on the physiological stress caused by Microcystis aeruginosa to zebrafish intestines

S Han, C Lu, M Qin, Y Wang, X Wu, X Xia, Y Li - Aquaculture, 2023 - Elsevier
Microcystis aeruginosa, the dominant species causing cyanobacterial blooms, poses a
serious threat to water environment security and development of aquaculture. The …

[HTML][HTML] Conessine as a novel inhibitor of multidrug efflux pump systems in Pseudomonas aeruginosa

T Siriyong, P Srimanote, S Chusri… - … and alternative medicine, 2017 - Springer
Background Holarrhena antidysenterica has been employed as an ethnobotanical plant for
the treatment of dysentery, diarrhoea, fever, and bacterial infections. Biological activities of …

Effects of different concentrations of Microcystis aeruginosa on the intestinal microbiota and immunity of zebrafish (Danio rerio)

H Qian, M Zhang, G Liu, T Lu, L Sun, X Pan - Chemosphere, 2019 - Elsevier
Microcystis aeruginosa is a primary species of toxin-producing cyanobacteria. This study
explored the effects of short-term exposure (96 h) to M. aeruginosa on the intestinal …

Pyrogallol downregulates the expression of virulence-associated proteins in Acinetobacter baumannii and showing anti-infection activity by improving non-specific …

G Abirami, R Alexpandi, S Sudhin, R Durgadevi… - International Journal of …, 2023 - Elsevier
Acinetobacter baumannii, a virulent uropathogen with widespread antibiotic resistance, has
arisen as a critical scientific challenge, necessitating the development of innovative …

[HTML][HTML] A Novel Infection Protocol in Zebrafish Embryo to Assess Pseudomonas aeruginosa Virulence and Validate Efficacy of a Quorum Sensing Inhibitor In Vivo

P Nogaret, F El Garah, AB Blanc-Potard - Pathogens, 2021 - mdpi.com
The opportunistic human pathogen Pseudomonas aeruginosa is responsible for a variety of
acute infections and is a major cause of mortality in chronically infected cystic fibrosis …

[HTML][HTML] Morin Protects Channel Catfish From Aeromonas hydrophila Infection by Blocking Aerolysin Activity

J Dong, Y Liu, N Xu, Q Yang, X Ai - Frontiers in microbiology, 2018 - frontiersin.org
Aeromonas hydrophila (A. hydrophila) is an opportunistic bacterial pathogen widely
distributed in the environments, particular aquatic environment. The pathogen can cause a …

[HTML][HTML] Weissella confusa DD_A7 pre-treatment to zebrafish larvae ameliorates the inflammation response against Escherichia coli O157: H7

DK Dey, SC Kang - Microbiological Research, 2020 - Elsevier
Increasing multidrug-resistant pathogenic bacterial contamination in the environment has
become the leading cause of food poisoning, resulting in life-threatening conditions due to …