[PDF][PDF] Meeting at the Crossroad between Obesity and Hepatic Carcinogenesis

K Arvanitakis, SP Papadakos, V Lekakis, T Koufakis… - 2023 - research.birmingham.ac.uk
The escalating global prevalence of obesity and its intricate association with the
development of hepatocellular carcinoma (HCC) pose a substantial challenge to public …

Meeting at the crossroad between obesity and hepatic carcinogenesis: unique pathophysiological pathways raise expectations for innovative therapeutic approaches

K Arvanitakis, SP Papadakos, V Lekakis… - International Journal of …, 2023 - mdpi.com
The escalating global prevalence of obesity and its intricate association with the
development of hepatocellular carcinoma (HCC) pose a substantial challenge to public …

Obesity, non-alcoholic fatty liver disease and hepatocellular carcinoma: Current status and therapeutic targets

Y Chen, W Wang, MP Morgan, T Robson… - Frontiers in …, 2023 - frontiersin.org
Obesity is a global epidemic and overwhelming evidence indicates that it is a risk factor for
numerous cancers, including hepatocellular carcinoma (HCC), the third leading cause of …

Molecular mechanisms regulating obesity-associated hepatocellular carcinoma

Y Rajesh, D Sarkar - Cancers, 2020 - mdpi.com
Obesity is a global, intractable issue, altering inflammatory and stress response pathways,
and promoting tissue adiposity and tumorigenesis. Visceral fat accumulation is correlated …

Obesity-associated mechanisms of hepatocarcinogenesis

R Karagozian, Z Derdák, G Baffy - Metabolism, 2014 - Elsevier
Obesity has been recognized as a key component of the metabolic syndrome, a cluster of
risk factors associated with diabetes and cardiovascular morbidity. In addition, obesity has …

Obesity management in the primary prevention of hepatocellular carcinoma

ERM Zunica, EC Heintz, CL Axelrod, JP Kirwan - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is an increasingly prevalent and deadly
disease driven in part by the rising obesity epidemic. Obesity causes HCC by initiating and …

[PDF][PDF] Obesity Management in the Primary Prevention of Hepatocellular Carcinoma. Cancers 2022, 14, 4051

ERM Zunica, EC Heintz, CL Axelrod, JP Kirwan - 2022 - academia.edu
Hepatocellular carcinoma (HCC) is the most frequent primary hepatic malignancy and a
leading cause of cancer-related death globally. HCC is associated with an indolent clinical …

How Does Obesity Cause Cancer?

KL Hoehn - Cancers, 2021 - mdpi.com
This series comprises 14 articles (5 original articles and 9 reviews) that investigate
connections between excess body mass and cancer risk or cancer treatment response. In …

Obesity and hepatocellular carcinoma

W Xu, J Yu - Liver pathophysiology, 2017 - Elsevier
Obesity is recognized as a major risk factor for multiple types of cancers, especially in
hepatocellular carcinoma (HCC). HCC is the most common form of liver cancer, which has a …

Hepatocellular carcinoma and obesity, type 2 diabetes mellitus, cardiovascular disease: causing factors, molecular links, and treatment options

C Zhang, S Liu, M Yang - Frontiers in Endocrinology, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, which will
affect more than a million people by the year 2025. However, current treatment options have …