Copolymers of N‐isopropylacrylamide (NIPAAm) and acrylic acid N‐hydroxysuccinimide
(NAS) were synthesized via free radical polymerization and conjugated with amine …

Purpose: Age related macular degeneration (AMD) remains a world leading cause of
irreversible central vision loss. In cases of late stage (wet) AMD, growth of blood vessels into …

There is significant interest in biomaterials that provide sustained release of therapeutic
molecules to the retina. Poly (N-isopropylacrylamide)(PNIPAAm)-based materials have …

We synthesized two thermoresponsive, bioactive cell scaffolds by decorating the backbone
of type I bovine collagen with linear chains of poly (N-isopropylacrylamide)(PNIPAAm), with …

Low patient compliance and poor bioavailability of ophthalmic medications are the main
limitations of topical eye drops. A potential solution to these disadvantages could be …

Hydrogel as an ocular drug delivery platform holds great potential. Hydrogels are three-
dimensional, hydrophilic, polymeric networks capable of absorbing large amounts of water …

Purpose:: The main objective is to characaterize thermo-responsive hydrogels as a novel
posterior segment drug delivery platform in the treatment of age-related macular …

Purpose To characterize thermoresponsive hydrogels (liquids at room temperature, gels at
body temperature) as a novel drug delivery platform to the posterior segment. Methods …

Purpose Age related macular degeneration (AMD) is a leading cause of blindness, and the
fastest growing source of visual impairment afflicting the elderly. Dry-AMD is fundamentally …

With the prevalence of eye diseases, such as cataracts, retinal degenerative diseases, and
glaucoma, different treatments including lens replacement, vitrectomy, and stem cell …