Substituted pyridine spleen tyrosine kinase (SYK) inhibitors

AM Haidle, SL Knowles, SD Kattar… - US Patent …, 2016 - Google Patents
2015-11-06 Assigned to MERCK SHARP & DOHME CORP. reassignment MERCK SHARP
& DOHME CORP. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

2-Pyridyl carboxamide-containing spleen tyrosine kinase (SYK) inhibitors

MD Altman, CE Bienstock, JW Butcher… - US Patent …, 2015 - Google Patents
6.432, 963 B1 8/2002 Hisamichi et al. WO WO2007028445 A1 3, 2007 6,589,950 B1 7/2003
Collingwood et al. WO WO2007042298 A1 4/2007 6,770,643 B2 8/2004 Cox et al. WO …

Phenyl carboxamide-containing spleen tyrosine kinase (SYK) inhibitors

MD Altman, ME Di Francesco, JM Ellis… - US Patent …, 2015 - Google Patents
5,710,129 A 1/1998 Lynch et al. 6,248,790 B1 6/2001 Uckun et al. 6.432, 963 B1 8/2002
Hisamichi et al. 6,589,950 B1 7/2003 Collingwood et al. 6,770,643 B2 8, 2004 Cox et al …

Amino-pyridine-containing spleen tyrosine kinase (SYK) inhibitors

ET Romeo, MR Machacek, BW Trotter, TA Miller… - US Patent …, 2014 - Google Patents
The invention provides certain amino-pyridine-containing compounds of the Formula (I) or
pharmaceutically accept able salts thereof, wherein R, R, R, R, R, R, R, R, R, and n are as …

Substituted phenyl-Spleen Tyrosine Kinase (Syk) inhibitors

AM Haidle, J Burch, D Guay, JY Gauthier… - US Patent …, 2016 - Google Patents
The invention provides certain Substituted phenyl compounds of the Formula (I) or
pharmaceutically acceptable salts thereof, wherein R', RRRR, and t are as defined herein …

Small molecule inhibitors of spleen tyrosine kinase (SYK)

J Zhang, R Singh, D Goff, T Kinoshita - US Patent 8,377,945, 2013 - Google Patents
HDKPOHYCWKULQC-UHFFFAOYSA-N 2-(3, 4-dimethoxyphenyl)-3-(4-fluoro-3-
methoxyanilino)-5H-imidazo [1, 2-b] pyrazole-7-carbonitrile Chemical compound C1= C …

3-pyridyl carboxamide-containing spleen tyrosine kinase (SYK) inhibitors

MD Altman, KK Childers, A Donofrio, JM Ellis… - US Patent …, 2015 - Google Patents
The invention provides certain 3-pyridyl carboxamide-con taining compounds of the Formula
(I)(I) or pharmaceutically acceptable salts thereof, wherein A and B are as defined herein …

Amino-pyrimidine-containing spleen tyrosine kinase (Syk) inhibitors

MR Machacek - US Patent 9,624,210, 2017 - Google Patents
The invention provides certain amino-pyrimidine-contain ing compounds. The invention also
provides pharmaceutical compositions comprising such compounds, and methods of using …

Amino-pyridine-containing spleen tyrosine kinase (syk) inhibitors

BM Andresen, NJ Anthony, TA Miller - US Patent App. 14/440,520, 2015 - Google Patents
0001. The present invention relates to certain amino-pyri dine-containing compounds of the
Formula (I)(also referred to herein as the “compounds of the Formula (I) or “com pounds of …

Substituted pyrrolidines as SYK inhibitors

KS Currie, Z Du, J Farand, JA Guerrero… - US Patent …, 2016 - Google Patents
2015-04-10 Assigned to GILEAD SCIENCES, INC. reassignment GILEAD SCIENCES, INC.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …