Background Free-water imaging identifies subtle changes in white matter microstructure
indicative of cellular and extracellular pathologies not visible on conventional stroke MRI …

In this study we explore the spatio‐temporal trajectory and clinical relevance of
microstructural white matter changes within and beyond subcortical stroke lesions detected …

Background The progression of FLAIR white matter hyperintensities (WMHs) on MRI heralds
vascular-mediated cognitive decline. Even before FLAIR WMH progression, adjacent normal …

Leukoaraiosis is a neuroimaging marker of small-vessel disease that is characterized by
high signal intensity on fluid-attenuated inversion recovery MRI. There is increasing …

Background and purpose The excess fluid as a result of vasogenic oedema and the
subsequent tissue cavitation obscure the microstructural characterisation of ischaemic tissue …

Objective To determine whether free water (FW) content, initially developed to correct
metrics derived from diffusion tensor imaging and recently found to be strongly associated …

The fate of subcortical diffusion-weighted imaging (DWI) lesions in stroke patients is highly
variable, ranging from complete tissue loss to no visible lesion on follow-up. Little is known …

BACKGROUND AND PURPOSE: We studied the evolution of brain water compartments
during the early stage of ischemic stroke. METHODS: Diffusion-weighted imaging was …

Objective To assess the role of net water uptake (NWU) in predicting outcomes in acute
ischemic stroke (AIS) patients. Methods A systematic review and meta-analysis were …

Brain imaging has seen considerable advances over the recent years. Both developments
and validation of advanced image acquisition techniques as well as post-processing and …