[HTML][HTML] The immunomodulatory and anti-inflammatory role of polyphenols

N Yahfoufi, N Alsadi, M Jambi, C Matar - Nutrients, 2018 - mdpi.com
This review offers a systematic understanding about how polyphenols target multiple
inflammatory components and lead to anti-inflammatory mechanisms. It provides a clear …

Dietary polyphenols suppress chronic inflammation by modulation of multiple inflammation-associated cell signaling pathways

I Jantan, MA Haque, L Arshad, H Harikrishnan… - The Journal of nutritional …, 2021 - Elsevier
The high failure rate of the reductionist approach to discover effective and safe drugs to treat
chronic inflammatory diseases has led scientists to seek alternative ways. Recently …

Oxidative stress and inflammation: what polyphenols can do for us?

T Hussain, B Tan, Y Yin, F Blachier… - Oxidative medicine …, 2016 - Wiley Online Library
Oxidative stress is viewed as an imbalance between the production of reactive oxygen
species (ROS) and their elimination by protective mechanisms, which can lead to chronic …

[PDF][PDF] Polyphenols, intracellular signalling and inflammation

C Santangelo, R Vari, B Scazzocchio… - … -istituto superiore di …, 2007 - researchgate.net
excessive inflammation is considered as a critical factor in many human diseases, including
cancer, obesity, type II diabetes, cardiovascular diseases, neurodegenerative diseases and …

Immunomodulatory; anti-inflammatory/antioxidant effects of polyphenols: A comparative review on the parental compounds and their metabolites

M Sobhani, MH Farzaei, S Kiani… - Food Reviews …, 2021 - Taylor & Francis
Polyphenols are a big family of phytochemicals that includes a wide range of natural
substances with various biological activities. Amongst these activities, the …

Intracellular signaling pathways modulated by phenolic compounds: application for new anti-inflammatory drugs discovery

G Costa, V Francisco, MC Lopes… - Current medicinal …, 2012 - ingentaconnect.com
Extensive research within the last two decades revealed that most chronic illnesses,
including cancer, neurological, autoimmune and cardiovascular diseases are mediated …

Regulation of inflammation and redox signaling by dietary polyphenols

I Rahman, SK Biswas, PA Kirkham - Biochemical pharmacology, 2006 - Elsevier
Reactive oxygen species (ROS) play a key role in enhancing the inflammation through the
activation of NF-κB and AP-1 transcription factors, and nuclear histone acetylation and …

[HTML][HTML] Immunomodulatory effects of dietary polyphenols

H Shakoor, J Feehan, V Apostolopoulos, C Platat… - Nutrients, 2021 - mdpi.com
Functional and nutraceutical foods provide an alternative way to improve immune function to
aid in the management of various diseases. Traditionally, many medicinal products have …

Role of antioxidants and natural products in inflammation

P Arulselvan, MT Fard, WS Tan… - Oxidative medicine …, 2016 - Wiley Online Library
Inflammation is a comprehensive array of physiological response to a foreign organism,
including human pathogens, dust particles, and viruses. Inflammations are mainly divided …

[HTML][HTML] Flavonoids, inflammation and immune system

FJ Pérez-Cano, M Castell - Nutrients, 2016 - mdpi.com
Flavonoids, including around 6000 phenolic compounds, are products of the secondary
metabolism of plants which can be a part of one's diet via the consumption of many edible …