The sine oculis homeobox (SIX) family of transcription factors as regulators of development and disease
JP Kumar - Cellular and Molecular Life Sciences, 2009 - Springer
The sine oculis homeobox (SIX) protein family is a group of evolutionarily conserved
transcription factors that are found in diverse organisms that range from flatworms to …
transcription factors that are found in diverse organisms that range from flatworms to …
[HTML][HTML] Six9 (Optx2), a new member of the six gene family of transcription factors, is expressed at early stages of vertebrate ocular and pituitary development
The Drosophila gene sine oculis (so) is a nuclear homeoprotein, which is required for eye
development. Several homologues of so have been found in vertebrates. We report here a …
development. Several homologues of so have been found in vertebrates. We report here a …
[HTML][HTML] Molecular cloning and embryonic expression of Xenopus Six homeobox genes
H Ghanbari, HC Seo, A Fjose, AW Brändli - Mechanisms of development, 2001 - Elsevier
Six genes are vertebrate homologues of the homeobox-containing gene sine oculis, which
plays an essential role in controlling Drosophila compound eye development. Here we …
plays an essential role in controlling Drosophila compound eye development. Here we …
[HTML][HTML] Expression pattern of cSix3, a member of the Six/sine oculis family of transcription factors
We describe the expression pattern of cSix3, a chick homologue of the murine Six3. cSix3
transcripts are expressed from presomitic stages in the most anterior portion of the neural …
transcripts are expressed from presomitic stages in the most anterior portion of the neural …
Six1: a critical transcription factor in tumorigenesis
W Wu, Z Ren, P Li, D Yu, J Chen… - … journal of cancer, 2015 - Wiley Online Library
In the past two decades, many studies have shown that sine oculis homeobox 1 (Six1) is a
powerful regulator of organogenesis and disease, with important roles in tumorigenesis; …
powerful regulator of organogenesis and disease, with important roles in tumorigenesis; …
[HTML][HTML] Expression of two zebrafish homologues of the murine Six3 gene demarcates the initial eye primordia
HC Seo, Ø Drivenes, S Ellingsen, A Fjose - Mechanisms of development, 1998 - Elsevier
The murine homeobox gene Six3 and its Drosophila homologue sine oculis both have
regulatory functions in eye development. We report the isolation and characterization of two …
regulatory functions in eye development. We report the isolation and characterization of two …
[HTML][HTML] Sine oculis, a member of the SIX family of transcription factors, directs eye formation
B Weasner, C Salzer, JP Kumar - Developmental biology, 2007 - Elsevier
The initiation of eye formation in all seeing animals is controlled by a group of selector
genes that together forms the retinal determination cascade. In Drosophila, mice and …
genes that together forms the retinal determination cascade. In Drosophila, mice and …
[HTML][HTML] Cloning and expression of xSix3, the Xenopus homologue of murine Six3
X Zhou, T Hollemann, T Pieler, P Gruss - Mechanisms of Development, 2000 - Elsevier
The vertebrate Six family of transcription factor genes are homologues of the fruitfly gene
sine oculis (so). Human, murine, avian and fish (medaka, zebrafish) homologues have …
sine oculis (so). Human, murine, avian and fish (medaka, zebrafish) homologues have …
Genomic cloning and characterization of the human homeobox gene SIX6 reveals a cluster of SIX genes in chromosome 14 and associates SIX6 hemizygosity with …
The Drosophila gene sine oculis (so), a nuclear homeoprotein that is required for eye
development, has several homologues in vertebrates (the SIX gene family). Among them …
development, has several homologues in vertebrates (the SIX gene family). Among them …
Six3 and Six6 activity is modulated by members of the groucho family
Six3 and Six6 are two genes required for the specification and proliferation of the eye field in
vertebrate embryos, suggesting that they might be the functional counterparts of the …
vertebrate embryos, suggesting that they might be the functional counterparts of the …
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- sine oculis transcription factors
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- eye formation transcription factors
- expression pattern transcription factors
- early stages transcription factors
- development and disease transcription factors
- pituitary development transcription factors