Endogenous retroviral sequences provide a molecular fossil record of ancient infections
whose analysis might illuminate mechanisms of viral extinction. A close relative of …

Mammalian genomes typically contain hundreds of thousands of endogenous retroviruses
(ERVs), derived from ancient retroviral infections. Using this molecular'fossil'record, we …

The resurrection of endogenous retroviruses from inactive molecular fossils has allowed the
investigation of interactions between extinct pathogens and their hosts that occurred millions …

Human endogenous retroviruses (HERVs), probably representing footprints of ancient germ‐
cell retroviral infections, occupy about 1% of the human genome. HERVs can influence …

Host genetic resistance to viral infection controls the pathogenicity and epidemic dynamics
of infectious diseases. Refrex-1 is a restriction factor against feline leukemia virus subgroup …

Primates emerged about 60 million years ago. Since that time various primate-targeting
retroviruses have integrated in the germ line of primate species, and some drifted to fixation …

Retroviruses infect a broad range of vertebrate hosts that includes amphibians, reptiles, fish,
birds and mammals. In addition, a typical vertebrate genome contains thousands of loci …

Retroviruses are members of the superfamily of retroelements, mobile genetic elements that
transpose via an RNA intermediate. However, retroviruses are distinct from other …

Human endogenous retroviruses (HERVs) are viral “fossils” in the human genome that
originated from the ancient integration of exogenous retroviruses. Although HERVs have …

Retroviruses exclusively infect vertebrates, causing a variety of diseases. The replication of
retroviruses requires reverse transcription and integration into host genomes. When …