Aim: To determine whether there is a long-term benefit of MRI-guided bilateral anterior
capsulotomy in the treatment of refractory schizophrenia. Methods: 116 patients (16 patients …

OBJECTIVE Despite its relatively low prevalence, schizophrenia has a high burden of illness
due to its lifelong effects and the fact that it is often refractory to psychotropic treatment. This …

BACKGROUND Psychiatric surgery is an important domain of functional neurosurgery and
involves deep brain stimulation (DBS) or lesional procedures performed for treatment …

Following the early studies of Moniz and Lima, psychosurgery had considerable scientific
credibility until the advent of modern antipsychotics in the mid 1950s. Thereafter …

Object The use of deep brain stimulation (DBS) has recently been expanded to the
investigational treatment of specific psychiatric disorders. Much like movement disorders, the …

Magnetic resonance-guided focused ultrasound (MRgFUS) anterior capsulotomy is a novel
treatment option for patients with refractory obsessive compulsive disorder (OCD) or major …

Schizophrenia is a chronic and progressive psychiatric disease that remains difficult to
manage in the 21st century. Current medical therapies have been able to give reprieve and …

Abstract WE DESCRIBE THE modern operative technique of magnetic resonance (MR)
image-guided stereotactic cingulotomy and discuss the indications, results, and …

Abstract In 1947, Spiegel and Wycis first reported the application of stereotactic techniques
to psychiatric surgery [29]. A few years later, such treatment was used systematically by …

TO THE EDITOR: We read with great interest the review by Mikell et al. 3(Mikell CB, Sinha S,
Sheth SA: Neurosurgery for schizophrenia: an update on pathophysiology and a novel …