Impact of Oxysterols in Age-Related Disorders and Strategies to Alleviate Adverse Effects
Oxysterols or cholesterol oxidation products are a class of molecules with the sterol moiety,
derived from oxidative reaction of cholesterol through enzymatic and non-enzymatic …
derived from oxidative reaction of cholesterol through enzymatic and non-enzymatic …
Cytotoxic effects of oxysterols associated with human diseases: Induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and …
Oxysterols resulting from spontaneous or enzymatic oxidation of cholesterol are present in
numerous foodstuffs and have been identified at increased levels in the plasma and the …
numerous foodstuffs and have been identified at increased levels in the plasma and the …
Involvement of oxysterols in age-related diseases and ageing processes
Ageing is accompanied by increasing vulnerability to major pathologies (atherosclerosis,
Alzheimer's disease, age-related macular degeneration, cataract, and osteoporosis) which …
Alzheimer's disease, age-related macular degeneration, cataract, and osteoporosis) which …
Oxysterols: A world to explore
A Otaegui-Arrazola, M Menendez-Carreño… - Food and chemical …, 2010 - Elsevier
Oxysterols (oxidized derivatives of cholesterol and phytosterols) can be generated in the
human organism through different oxidation processes, some requiring enzymes …
human organism through different oxidation processes, some requiring enzymes …
Free radical attack on cholesterol: oxysterols as markers of oxidative stress and as bioactive molecules
F Micheletta, L Iuliano - Immunology, Endocrine & Metabolic …, 2006 - ingentaconnect.com
Oxysterols are oxygenated derivatives of cholesterol with a very short life-time relative to
cholesterol. Oxysterols are present in nanomolar concentrations in biological fluids …
cholesterol. Oxysterols are present in nanomolar concentrations in biological fluids …
Therapeutic Applications of Oxysterols and Derivatives in Age-Related Diseases, Infectious and Inflammatory Diseases, and Cancers
Oxysterols, resulting from the oxidation of cholesterol, are formed either by autoxidation,
enzymatically, or by both processes. These molecules, which are provided in more or less …
enzymatically, or by both processes. These molecules, which are provided in more or less …
Oxysterols are potential physiological regulators of ageing
P de Medina, S Silvente-Poirot, M Poirot - Ageing Research Reviews, 2022 - Elsevier
Delaying and even reversing ageing is a major public health challenge with a tremendous
potential to postpone a plethora of diseases including cancer, metabolic syndromes and …
potential to postpone a plethora of diseases including cancer, metabolic syndromes and …
Dietary phytochemicals in the protection against oxysterol-induced damage
A Cilla, A Alegria, A Attanzio, G Garcia-Llatas… - Chemistry and physics …, 2017 - Elsevier
The intake of fruits and vegetables is associated with reduced incidence of many chronic
diseases. These foods contain phytochemicals that often possess antioxidant and free …
diseases. These foods contain phytochemicals that often possess antioxidant and free …
A comprehensive review on oxysterols and related diseases
A Samadi, S Sabuncuoglu, M Samadi… - Current medicinal …, 2021 - ingentaconnect.com
The present review aims to provide a complete and comprehensive summary of current
literature relevant to oxysterols and related diseases. Oxidation of cholesterol leads to the …
literature relevant to oxysterols and related diseases. Oxidation of cholesterol leads to the …
Oxysterols as Biomarkers of Aging and Disease
Oxysterols derive from either enzymatic or non-enzymatic oxidation of cholesterol. Even
though they are produced as intermediates of bile acid synthesis pathway, they are …
though they are produced as intermediates of bile acid synthesis pathway, they are …