Coumarin derivates have been proposed as a potential treatment for metabolic-dysfunction-
associated fatty liver disease (MAFLD). However, the mechanisms underlying their …

This study aimed to determine the lipid-lowering effect of esculetin (6, 7-dihydroxycoumarin),
a coumarin derivative, using a cell model of steatosis induced by a mixture of free fatty acids …

Aims: Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver
diseases. However, there are no approved pharmacotherapies for the treatment of NAFLD …

Resveratrol (RES), a natural polyphenol phytoalexin, has been reported to attenuate
nonalcoholic fatty liver disease (NAFLD). However, its roles on protection of liver from …

This study investigated the effects and mechanism of esculetin (6, 7-dihydroxycoumarin) on
non-alcoholic fatty liver in diabetic mice fed high-fat diet (HFD). The diabetic mice model was …

Non-alcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease,
encompassing a range of conditions caused by lipid deposition within liver cells, and is also …

Aim To investigate the therapeutic effect and potential mechanisms of the natural flavonoid
quercetin‐3‐O‐β‐D‐glucuronide (Q3GA) against lipid metabolism disorder in free fatty acid …

The prevalence of nonalcoholic steatohepatitis (NASH), characterized by fatty liver, oxidative
injury, and inflammation, has considerably increased in the recent years. Due to the …

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide. To date, no medication has been approved to treat NAFLD. In this study, we …

The prevalence of non-alcoholic fatty liver disease (NAFLD) is one of the leading causes of
chronic liver diseases worldwide. This study examined the potential protective effects of a …