An insight into non-integrative gene delivery approaches to generate transgene-free induced pluripotent stem cells

KK Haridhasapavalan, MP Borgohain, C Dey, B Saha… - Gene, 2019 - Elsevier
Over a decade ago, a landmark study that reported derivation of induced Pluripotent Stem
Cells (iPSCs) by reprogramming fibroblasts has transformed stem cell research attracting …

Experimental approaches for the generation of induced pluripotent stem cells

CA Sommer, G Mostoslavsky - Stem Cell Research & Therapy, 2010 - Springer
Derivation of autologous induced pluripotent stem cells (iPSCs) through direct
reprogramming of easily accessible somatic cells holds the potential to transform the field of …

New strategies to generate induced pluripotent stem cells

J O'Malley, K Woltjen, K Kaji - Current Opinion in Biotechnology, 2009 - Elsevier
Direct reprogramming of somatic cells to a pluripotent state, substantiated only three years
prior, is one of the most rapidly developing areas of stem cell research. The generation of …

An insight into DNA-free reprogramming approaches to generate integration-free induced pluripotent stem cells for prospective biomedical applications

MP Borgohain, KK Haridhasapavalan, C Dey… - Stem Cell Reviews and …, 2019 - Springer
More than a decade ago, a pioneering study reported generation of induced Pluripotent
Stem Cells (iPSCs) by ectopic expression of a cocktail of reprogramming factors in …

Progress and promise towards safe induced pluripotent stem cells for therapy

A Seifinejad, M Tabebordbar, H Baharvand… - Stem Cell Reviews and …, 2010 - Springer
The recent generation of induced pluripotent stem cells (iPSCs) from somatic cells provides
an invaluable resource for drug or toxicology screening, medical research, and patient …

An overview of reprogramming approaches to derive integration-free induced pluripotent stem cells for prospective biomedical applications

C Dey, K Raina, KK Haridhasapavalan, M Thool… - Recent advances in …, 2021 - Elsevier
The remarkable discovery of the derivation of induced pluripotent stem cells (iPSCs)
heralded the development of a new technological platform for therapeutic applications in …

Ten years of progress and promise of induced pluripotent stem cells: historical origins, characteristics, mechanisms, limitations, and potential applications

AE Omole, AOJ Fakoya - PeerJ, 2018 - peerj.com
The discovery of induced pluripotent stem cells (iPSCs) by Shinya Yamanaka in 2006 was
heralded as a major breakthrough of the decade in stem cell research. The ability to …

An overview on promising somatic cell sources utilized for the efficient generation of induced pluripotent stem cells

A Ray, JM Joshi, PK Sundaravadivelu, K Raina… - Stem Cell Reviews and …, 2021 - Springer
Abstract Human induced Pluripotent Stem Cells (iPSCs) have enormous potential in
understanding developmental biology, disease modeling, drug discovery, and regenerative …

Inducing pluripotency in vitro: recent advances and highlights in induced pluripotent stem cells generation and pluripotency reprogramming

IK Rony, A Baten, JA Bloomfield, ME Islam… - Cell …, 2015 - Wiley Online Library
Induced pluripotent stem cells (iPSC s) are considered patient‐specific counterparts of
embryonic stem cells as they originate from somatic cells after forced expression of …

Guidelines and techniques for the generation of induced pluripotent stem cells

N Maherali, K Hochedlinger - Cell stem cell, 2008 - cell.com
Direct reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) provides an
invaluable resource for regenerative medicine, enabling the generation of patient-specific …