Staphylococcus aureus has developed resistance to antimicrobials since their first use. The
S. aureus major facilitator superfamily (MFS) efflux pump Tet (K) contributes to resistance to …

The emergence of multidrug-resistant Staphylococcus aureus coupled with a declining
output of new antibiotic treatment options from the pharmaceutical industry is a growing …

Background Bacterial resistance to multiple drugs has recently emerged as a serious health
problem. Concomitantly, the characterization of new substances with potential antimicrobial …

aminothiophene derivatives (2AT) in which the thiophene ring is fused with a cycloalkyl or a
N‐acylated piperidine ring by positions 5 and 6 and carrying a 3‐carbethoxy group were …

Objectives To perform an in silico prediction of drug efflux pumps (EPs) in Staphylococcus
pseudintermedius and investigate their role in conferring resistance to antibiotic and biocidal …

Background and objectives Staphylococcus aureus is an opportunistic pathogen that causes
wide range of nosocomial and community-acquired infections which have spread worldwide …

The increasing emergence of antimicrobial resistance in staphylococcal bacteria is a major
health threat worldwide due to significant morbidity and mortality resulting from their …

Introduction: Infectious diseases have been responsible for an increasing number of deaths
worldwide. Staphylococcus aureus has been recognized as one of the most notable …

Staphylococcus aureus biofilms are involved in a wide range of infections that are extremely
difficult to treat with conventional antibiotic therapy. We aimed to identify potentiators of …

Background The rapid emergence of antimicrobial resistance among Gram-positive
organisms, especially staphylococci, has become a serious clinical challenge. Efflux …