[HTML][HTML] Development of a fluorescence in situ hybridization probe for detecting IKZF1 deletion mutations in patients with acute lymphoblastic leukemia
J Hashiguchi, M Onozawa, S Oguri, S Fujisawa… - The Journal of Molecular …, 2018 - Elsevier
Intragenic deletion of IKZF1 is a recurrent genomic alteration in acute lymphoblastic
leukemia. The deletions are mediated by illegitimate variable (diversity) joining …
leukemia. The deletions are mediated by illegitimate variable (diversity) joining …
[HTML][HTML] IKZF1 deletions with COBL breakpoints are not driven by RAG-mediated recombination events in acute lymphoblastic leukemia
Abstract IKZF1 deletion (ΔIKZF1) is an important predictor of relapse in both childhood and
adult B-cell precursor acute lymphoblastic leukemia (B-ALL). Previously, we revealed that …
adult B-cell precursor acute lymphoblastic leukemia (B-ALL). Previously, we revealed that …
Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1–positive acute lymphoblastic …
I Iacobucci, CT Storlazzi, D Cilloni… - Blood, The Journal …, 2009 - ashpublications.org
The BCR-ABL1 fusion gene defines the subgroup of acute lymphoblastic leukemia (ALL)
with the worst clinical prognosis. To identify oncogenic lesions that combine with BCR-ABL1 …
with the worst clinical prognosis. To identify oncogenic lesions that combine with BCR-ABL1 …
[引用][C] Quantitative detection of IKZF1 deletion by digital PCR in patients with acute lymphoblastic leukemia.
J Hashiguchi, M Onozawa, K Okada… - … Journal of Laboratory …, 2018 - europepmc.org
Quantitative detection of IKZF1 deletion by digital PCR in patients with acute lymphoblastic
leukemia. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC …
leukemia. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC …
High frequency of IKZF1 genetic alterations in adult patients with B‐cell acute lymphoblastic leukemia
K Tokunaga, S Yamaguchi, E Iwanaga… - European journal of …, 2013 - Wiley Online Library
Alterations in the IKZF1 gene are associated with poor prognosis in pediatric B‐cell acute
lymphoblastic leukemia (B‐ALL). We examined the relationship between IKZF1 alterations …
lymphoblastic leukemia (B‐ALL). We examined the relationship between IKZF1 alterations …
Detection of Pathogenic Isoforms of IKZF1 in Leukemic Cell Lines and Acute Lymphoblastic Leukemia Samples: Identification of a Novel Truncated IKZF1 Transcript …
Simple Summary Abnormal RNA splicing plays a fundamental role in leukemogenesis in
acute lymphoblastic leukemia (ALL). Many cases of high-risk B-cell ALL cases, including …
acute lymphoblastic leukemia (ALL). Many cases of high-risk B-cell ALL cases, including …
The application of targeted RNA sequencing for the analysis of fusion genes, gene mutations, IKZF1 intragenic deletion, and CRLF2 overexpression in acute …
Z Zhang, Y Jing, B Chen, H Zhang, T Liu… - International Journal …, 2024 - Wiley Online Library
Introduction Acute lymphoblastic leukemia (ALL) is characterized by highly genetic
heterogeneity, owing to recurrent fusion genes, gene mutations, intragenic deletion, and …
heterogeneity, owing to recurrent fusion genes, gene mutations, intragenic deletion, and …
[HTML][HTML] COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia
Abstract IKZF1 deletion (ΔIKZF1) is an important predictor of relapse in childhood B-cell
precursor acute lymphoblastic leukemia. Because of its clinical importance, we previously …
precursor acute lymphoblastic leukemia. Because of its clinical importance, we previously …
RCSD1‐ABL1 Translocation Associated with IKZF1 Gene Deletion in B‐Cell Acute Lymphoblastic Leukemia
S Kamran, G Raca, K Nazir - Case Reports in Hematology, 2015 - Wiley Online Library
The RCSD1 gene has recently been identified as a novel gene fusion partner of the ABL1
gene in cases of B‐cell Acute Lymphoblastic Leukemia (B‐ALL). The RCSD1 gene is …
gene in cases of B‐cell Acute Lymphoblastic Leukemia (B‐ALL). The RCSD1 gene is …
Highly sensitive MRD tests for ALL based on the IKZF1 Δ3–6 microdeletion
NC Venn, VHJ Van Der Velden, M de Bie, E Waanders… - Leukemia, 2012 - nature.com
Current clinical trials for patients with acute lymphoblastic leukemia (ALL) depend upon the
measurement of minimal residual disease (MRD) at early stages of therapy to determine the …
measurement of minimal residual disease (MRD) at early stages of therapy to determine the …