Cellular circadian clocks in mood disorders
MJ McCarthy, DK Welsh - Journal of biological rhythms, 2012 - journals.sagepub.com
Bipolar disorder (BD) and major depressive disorder (MDD) are heritable neuropsychiatric
disorders associated with disrupted circadian rhythms. The hypothesis that circadian clock …
disorders associated with disrupted circadian rhythms. The hypothesis that circadian clock …
Circadian neurogenetics of mood disorders
J Mendoza, G Vanotti - Cell and tissue research, 2019 - Springer
Mood state alterations are often accompanied by disruptions of daily rhythms of physiology.
Circadian rhythms of physiology are controlled by a central clock harbored in the …
Circadian rhythms of physiology are controlled by a central clock harbored in the …
Role for the Clock gene in bipolar disorder
CA McClung - Cold Spring Harbor symposia on quantitative …, 2007 - symposium.cshlp.org
Nearly all patients with bipolar disorder have severely disrupted circadian rhythms.
Treatment with mood stabilizers can restore these daily rhythms, and this is correlated with …
Treatment with mood stabilizers can restore these daily rhythms, and this is correlated with …
When brain clocks lose track of time: cause or consequence of neuropsychiatric disorders
JS Menet, M Rosbash - Current opinion in neurobiology, 2011 - Elsevier
Patients suffering from neuropsychiatric disorders often exhibit a loss of regulation of their
biological rhythms which leads to altered sleep/wake cycle, body temperature rhythm and …
biological rhythms which leads to altered sleep/wake cycle, body temperature rhythm and …
Clock genes at the heart of depression
DJ Kennaway - Journal of Psychopharmacology, 2010 - journals.sagepub.com
The rhythms of life are ever pervasive, touching almost every aspect of our lives. We are
finely tuned to the cycle of light and dark, so that we normally sleep during the night and are …
finely tuned to the cycle of light and dark, so that we normally sleep during the night and are …
Circadian rhythms in mood disorders
MR Scott, CA McClung - Circadian clock in brain health and disease, 2021 - Springer
Altered behavioral rhythms are a fundamental diagnostic feature of mood disorders. Patients
report worse subjective sleep and objective measures confirm this, implicating a role for …
report worse subjective sleep and objective measures confirm this, implicating a role for …
How might circadian rhythms control mood? Let me count the ways...
CA McClung - Biological psychiatry, 2013 - Elsevier
Mood disorders are serious diseases that affect a large portion of the population. There have
been many hypotheses put forth over the years to explain the development of major …
been many hypotheses put forth over the years to explain the development of major …
Knockdown of Clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior
S Mukherjee, L Coque, JL Cao, J Kumar… - Biological …, 2010 - Elsevier
BACKGROUND: Circadian rhythm abnormalities are strongly associated with bipolar
disorder; however the role of circadian genes in mood regulation is unclear. Previously, we …
disorder; however the role of circadian genes in mood regulation is unclear. Previously, we …
Circadian clocks and mood-related behaviors
U Albrecht - Circadian clocks, 2013 - Springer
Circadian clocks are present in nearly all tissues of an organism, including the brain. The
brain is not only the site of the master coordinator of circadian rhythms located in the …
brain is not only the site of the master coordinator of circadian rhythms located in the …
Mood‐related central and peripheral clocks
KD Ketchesin, D Becker‐Krail… - European Journal of …, 2020 - Wiley Online Library
Mood disorders, including major depression, bipolar disorder, and seasonal affective
disorder, are debilitating disorders that affect a significant portion of the global population …
disorder, are debilitating disorders that affect a significant portion of the global population …