Depressed natural killer cell activity in patients with hepatocellular carcinoma in vitro effects of interferon and levamisole

K Son, M Kew, AR Rabson - Cancer, 1982 - Wiley Online Library
Enriched lymphocytes from patients with primary hepatocellular carcinoma showed
considerably reduced natural cytotoxicity against two established hepatoma cell lines and …

Defective function of lymphokine-activated killer cells and natural killer cells in patients with hepatocellular carcinoma

T Saibara, S Onishi, H Sakaeda, Y Yamamoto - Hepatology, 1989 - journals.lww.com
Lymphokine-activated killer activity and natural killer activity in hepatocellular carcinoma
patients were assessed. Maximum lymphokine-activated killer activity was induced at 3 to 5 …

Natural killer cell activity in hepatocellular carcinoma: in vitro and in vivo responses to interferon

AA Dunk, D Novick, HC Thomas - Scandinavian journal of …, 1987 - Taylor & Francis
We have measured natural killer (NK) cell activity in patients with hepatocellular carcinoma
(HCC) and have examined the effects of in vitro and in vivo administration of a-interferon …

Natural killer activity in patients with biopsy-proven liver disease.

S Serdengecti, DB Jones, G Holdstock… - Clinical and …, 1981 - ncbi.nlm.nih.gov
Most previous studies of lymphocyte-mediated cytotoxicity to animal and human hepatocytes
have not taken into account the ability to human lymphoid cells to kill spontaneously cultured …

Natural killer and activated killer activities in chronic liver disease and hepatocellular carcinoma: evidence for a decreased lymphokine-induced activity of effector cells …

H Hirofuji, S Kakumu, A Fuji, Y Ohtani… - Clinical and …, 1987 - ncbi.nlm.nih.gov
Natural killer (NK) and activated killer (AK) cells appear to be important in
immunoregulation, elimination of virus-infected cells and resistance to tumours. NK activity …

Decreased natural killer cell activity and interferon production by leucocytes in patients with adenocarcinoma of the pancreas.

K Funa, B Nilsson, G Jacobsson, GV Alm - British journal of cancer, 1984 - ncbi.nlm.nih.gov
Natural killer (NK) cells may play an important role in immune surveillance against tumours
(Herberman, 1982) and interferons (IFN) may serve as modulators of their cytolytic activity …

Defects in natural killer cell activity and interferon response in human lung carcinoma and malignant melanoma

WL Sibbitt Jr, AD Bankhurst, AJ Jumonville, JH Saiki… - Cancer Research, 1984 - AACR
The natural killer (NK) activity of peripheral blood mononuclear cells from 25 patients with
squamous cell carcinoma of the lung, malignant melanoma, or epitheloid cancers of the …

Lysis of primary hepatic tumours by lymphokine activated killer cells.

KH Hsieh, SY Shu, CS Lee, CT Chu, CS Yang… - Gut, 1987 - gut.bmj.com
Lymphokine activated killer cell is a newly described lytic system against a variety of solid
tumours and is distinct in several respects from the classic cytolytic T cell and the natural …

Depressed spontaneous natural killing and interferon augmentation in patients with malignant lymphoma

CM Hawrylowicz, RC Rees, BW Hancock… - European Journal of …, 1982 - Elsevier
Abstract A substantial proportion (44%) of peripheral blood lymphocyte samples from 41
patients with malignant lymphoma have been shown to have depressed or undetectable …

Effect of various interferons on the spontaneous cytotoxicity exerted by lymphocytes from normal and tumor-bearing patients

MA Lucero, WH Fridman, MA Provost, C Billardon… - Cancer Research, 1981 - AACR
Natural killer cell activity, which represents the spontaneous cytotoxicity of lymphocytes
toward tumor cells, has been measured in 173 tumor-bearing patients and 25 healthy …