The definitive treatment for end-stage organ failure is orthotopic transplantation. However,
the demand for transplantation far exceeds the number of available donor organs. A …

Organ transplantation in an orthotopic location is the current treatment for end-stage organ
failure. However, the need for transplantable organs far exceeds the number of available …

Organ transplantation is now a well-established procedure for the treatment of end-stage
organ failure due to various causes, but is a victim of its own success in that there is a …

End‐stage organ failure is a devastating problem with limited therapeutic options. The
definitive treatment is orthotropic transplantation, however, there exists a severe shortage of …

With the advent of whole organ decellularization, extracellular matrix scaffolds suitable for
organ engineering were generated from numerous tissues, including the heart, lung, liver …

The search for alternatives to allogeneic organ transplantation continues. Important
milestones have been achieved in organ bioengineering with the use of decellularized …

Decellularization is the process by which cells are discharged from tissues/organs, but all of
the essential cues for cell preservation and homeostasis are retained in a three-dimensional …

Whole-organ decellularization and tissue engineering approaches have made significant
inroads during recent years. If proven to be successful and clinically viable, it is highly likely …

Decellularized tissues, in which the extracellular matrix is isolated, have broad applications
as implantable biomaterials and/or biological scaffolds for tissue repair, and show good …

The shortage of donor organs for transplantation remains a continued problem for patients
with irreversible end-stage organ failure. Tissue engineering and regenerative medicine …