[HTML][HTML] Elucidating the toxicity mechanism of AFM2 and the protective role of quercetin in albino mice

M Onur, E Yalçın, K Çavuşoğlu, A Acar - Scientific Reports, 2023 - nature.com
Abstract Aflatoxin M2 (AFM2) is a type of mycotoxin detected in milk or dairy products from
animals consuming contaminated feed. In this study, the toxicity mechanism of AFM2 and …

[HTML][HTML] Toxicity mechanisms of aflatoxin M1 assisted with molecular docking and the toxicity-limiting role of trans-resveratrol

İ Güç, E Yalçin, K Çavuşoğlu, A Acar - Scientific Reports, 2022 - nature.com
In this study, AFM1 toxicity and the protective role of trans-resveratrol (t-rsv) against this
toxicity were investigated with the help of multiple parameters in albino mice. As a result …

[HTML][HTML] Ferulic acid prevents aflatoxin B1-induced liver injury in rats via inhibiting cytochrome P450 enzyme, activating Nrf2/GST pathway and regulating …

X Wang, Y He, J Tian, I Muhammad, M Liu, C Wu… - Ecotoxicology and …, 2021 - Elsevier
Abstract Aflatoxin B1 (AFB1) causes oxidative stress and hepatocyte apoptosis through its
epoxidized metabolite AFBO, which is catalyzed by CYP450 enzymes. Ferulic acid (FA) is a …

[HTML][HTML] The intervention and mechanism of action for aloin against subchronic aflatoxin b1 induced hepatic injury in rats

H Hua, J Sheng, Y Cui, W Zhang, B Hu… - International Journal of …, 2021 - mdpi.com
As a class of difurancoumarin compounds with similar structures, aflatoxins (AF) are
commonly found in the environment, soil, and food crops. AF pose a serious threat to the …

[HTML][HTML] Metabolomic analysis reveals the mechanisms of hepatotoxicity induced by aflatoxin M1 and ochratoxin A

YN Gao, CQ Wu, JQ Wang, N Zheng - Toxins, 2022 - mdpi.com
Aflatoxin M1 (AFM1) is the only toxin with the maximum residue limit in milk, and ochratoxin
A (OTA) represents a common toxin in cereals foods. It is common to find the co-occurrence …

Caffeic acid phenethyl ester modulates aflatoxin B1‐induced hepatotoxicity in rats

M Akçam, R Artan, A Yilmaz, S Ozdem… - Cell biochemistry …, 2013 - Wiley Online Library
Aflatoxin B1 (AFB1) is the most potent of the mycotoxins and is widely observed in nutrition
abnormalities. There are some studies suggesting oxidative stress‐induced toxic changes …

Synergistic effect of black tea and curcumin in improving the hepatotoxicity induced by aflatoxin B1 in rats

AA Alm-Eldeen, MH Mona, AA Shati… - … and industrial health, 2015 - journals.sagepub.com
Aflatoxin B1 (AFB1) is a toxic compound commonly found as a contaminant in human food. It
is carcinogenic due its potential in inducing the oxidative stress and distortion of the most …

Hepatoprotective effects of chlorogenic acid on mice exposed to aflatoxin B1: Modulation of oxidative stress and inflammation

K Cheng, J Niu, J Zhang, Y Qiao, G Dong, R Guo… - Toxicon, 2023 - Elsevier
Abstract Aflatoxin B1 (AFB1) is widely distributed in crops and feeds, and ingestion of AFB1-
contaminated crops is harmful to human/animal health. This study was designed to …

[HTML][HTML] Evaluation of neuroprotective effects of quercetin against aflatoxin B1-intoxicated mice

E Gugliandolo, AF Peritore, R D'Amico, P Licata… - Animals, 2020 - mdpi.com
Simple Summary Aflatoxin B1 (AFB1) is a mycotoxin commonly present in feed,
characterized by several toxic effects. AFB1 has been described as being responsible for …

Therapeutic detoxification of quercetin for aflatoxin B1-related toxicity: Roles of oxidative stress, inflammation, and metabolic enzymes

C Dai, G Sharma, G Liu, J Shen, B Shao, Z Hao - Environmental Pollution, 2024 - Elsevier
Aflatoxins (AFTs), a type of mycotoxin mainly produced by Aspergillus parasiticus and
Aspergillus flavus, could be detected in food, feed, Chinese herbal medicine, grain crops …