The mitochondrial inner membrane lost its selectivity for the transport of solutes after
reaction of hydrophobic sulfhydryl groups with alkylating agents (maleimide derivatives) …

The effect of some thiol alkylating agents (N-substituted maleimide derivatives) on the
permeability of the mitochondrial inner membrane was investigated. Several experimental …

The content of mitochondrial membrane protein thiol groups accessible to react with the
monofunctional thiol reagents mersalyl or N-ethylmaleimide (NEM) was determined using …

Mitochondria possess a semipermeable membrane with properties similar to the cell
membrane. Despite the presence of a limiting membrane, mitochondria swell approximately …

Treatment of the inner membrane matrix fraction of rat liver mitochondria with the nonionic
detergent Lubrol WX solubilized about 70% of the total protein and 90% or more of the …

Results-The dependence of the uptake of labeled CMS or CMB by intact heart mitochondria
on the composition of the suspending medium is shown in Table I. CMS reacts with between …

Respiratory-inhibited liver mitochondria underwent a passive swelling of" large amplitude"
when the permeability of the mitochondrial membrane to cations and anions was increased …

Publisher Summary This chapter discusses the structural and functional organization of
mitochondrial membranes. The mitochondrial structure was considered to be two chambers …

RESULTS Table I summarizes the swelling changes and activity associated with the
substrates under study. Glutamate and succinate give rise to swelling changes which do not …

A study was made of the effects of various types of detergents on the swelling of isolated
mitochondria and on mitochondrial ATPases which are activated by Mg or DNP respectively …