Ginsenoside Rg5 attenuates hypoxia‐induced cardiomyocyte apoptosis via regulating the Akt pathway

C Wang, C Huang, J Wang, J Ye, Z Xue… - Chemical Biology & …, 2023 - Wiley Online Library
Ginsenoside Rg5 has been implicated in a variety of diseases. However, it is unknown
whether Ginsenoside Rg5 can protect against hypoxia‐induced neonatal rat cardiomyocytes …

The structure-activity relationship of ginsenosides on hypoxia-reoxygenation induced apoptosis of cardiomyocytes

R Feng, J Liu, Z Wang, J Zhang, C Cates… - Biochemical and …, 2017 - Elsevier
Ginsenosides have been studied extensively in recent years due to their therapeutic effects
in cardiovascular diseases. While most studies examined the different ginsenosides …

Ginsenoside Rg1 protects cardiomyocytes from hypoxia-induced injury through the PI3K/AKT/mTOR pathway

L Qin, S Fan, R Jia, Y Liu - Die Pharmazie-An International …, 2018 - ingentaconnect.com
Aim: Myocardial ischemia (MI) is a leading cause of morbidity and mortality which makes the
prevention and control of MI tremendously important. We aimed to explore the functional …

Ginsenoside Rg1 ameliorates diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress‐induced apoptosis in a streptozotocin‐induced diabetes rat model

H Yu, J Zhen, Y Yang, J Gu, S Wu… - Journal of Cellular and …, 2016 - Wiley Online Library
Ginsenoside Rg1 has been demonstrated to have cardiovascular protective effects.
However, whether the cardioprotective effects of ginsenoside Rg1 are mediated by …

Ginsenoside rb1 protects neonatal rat cardiomyocytes from hypoxia/ischemia induced apoptosis and inhibits activation of the mitochondrial apoptotic pathway

X Yan, J Tian, H Wu, Y Liu, J Ren… - Evidence‐Based …, 2014 - Wiley Online Library
Aim. To investigate the effect of Ginsenoside Rb1 (GS‐Rb1) on hypoxia/ischemia (H/I) injury
in cardiomyocytes in vitro and the mitochondrial apoptotic pathway mediated mechanism …

[HTML][HTML] Oral administration of Ginsenoside Rg1 prevents cardiac toxicity induced by doxorubicin in mice through anti-apoptosis

C Zhu, Y Wang, H Liu, H Mu, Y Lu, J Zhang, J Huang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Although Ginsenoside Rg1 has been reported to have protective cardiac effects, its
effects on cardiac toxicity induced by doxorubicin needs to be studied. The present study …

[HTML][HTML] Notoginsenoside R 1 prevents H9c2 cardiomyocytes apoptosis against hypoxia/reoxygenation via the ERs/PI3K/Akt pathway

G Li, X Xing, Y Luo, X Deng, S Lu, S Tang, G Sun… - RSC …, 2018 - pubs.rsc.org
Notoginsenoside R1 (NGR1) is separate from Panax notoginsenosides (PNS), and plays a
role similar to phytoestrogen in preventing and treating cardiovascular diseases. However …

Ginsenoside Rh2 mitigates myocardial damage in acute myocardial infarction by regulating pyroptosis of cardiomyocytes

H Peng, L Chen, Y Deng, X Liao… - Clinical and Experimental …, 2023 - Taylor & Francis
Background Acute myocardial infarction (AMI) is one of the most important causes of
mortality among patients with cardiovascular disease. Ginsenoside Rh2 plays a protective …

[HTML][HTML] Ginsenoside Rg3 attenuates myocardial ischemia/reperfusion injury via Akt/endothelial nitric oxide synthase signaling and the B‑cell lymphoma/B‑cell …

Y Wang, Z Hu, B Sun, J Xu… - Molecular medicine …, 2015 - spandidos-publications.com
Previous studies have suggested that ginsenoside Rg3 (GSRg3) extract from the medicinal
plant Panax ginseng, may increase nitric oxide production via increases in the …

[HTML][HTML] Ginsenoside compound-Mc1 attenuates oxidative stress and apoptosis in cardiomyocytes through an AMP-activated protein kinase–dependent mechanism

S Hong, HJ Hwang, JW Kim, JA Kim, YB Lee… - Journal of Ginseng …, 2020 - Elsevier
Abstract Background Ginsenoside compound-Mc1 (Mc1) is a member of the deglycosylated
ginsenosides obtained from ginseng extract. Although several ginsenosides have a …