[HTML][HTML] The impact of TRPV1 on cancer pathogenesis and therapy: a systematic review

L Li, C Chen, C Chiang, T Xiao, Y Chen… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
The transient receptor potential cation channel subfamily V member 1 (TRPV1) is a
transmembrane protein that can be activated by various physical and chemical stimuli and is …

TRPV2: a cancer biomarker and potential therapeutic target

KS Siveen, PB Nizamuddin, S Uddin… - Disease …, 2020 - Wiley Online Library
The Transient Receptor Potential Vanilloid type‐2 (TRPV2) channel exhibits oncogenicity in
different types of cancers. TRPV2 is implicated in signaling pathways that mediate cell …

[HTML][HTML] TRPV6 as a target for cancer therapy

JM Stewart - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Two decades ago a class of ion channels, hitherto unsuspected, was discovered. In
mammals these Transient Receptor Potential channels (TRPs) have not only expanded in …

[HTML][HTML] Transient receptor potential ion-channel subfamily V member 4: a potential target for cancer treatment

S Yu, S Huang, Y Ding, W Wang, A Wang, Y Lu - Cell death & disease, 2019 - nature.com
The transient receptor potential ion-channel superfamily consists of nonselective cation
channels located mostly on the plasma membranes of numerous animal cell types, which …

[HTML][HTML] Loss of TRPV2 homeostatic control of cell proliferation drives tumor progression

S Liberati, MB Morelli, C Amantini, V Farfariello… - Cells, 2014 - mdpi.com
Herein we evaluate the involvement of the TRPV2 channel, belonging to the Transient
Receptor Potential Vanilloid channel family (TRPVs), in development and progression of …

[HTML][HTML] Pharmacological inhibition of TRPV4 channel suppresses malignant biological behavior of hepatocellular carcinoma via modulation of ERK signaling …

Y Fang, G Liu, C Xie, K Qian, X Lei, Q Liu, G Liu… - Biomedicine & …, 2018 - Elsevier
TRPV4 (transient receptor potential vanilloid 4), a member of the TRP superfamily, has been
reported to correlate with several different forms of cancers. However, the role of TRPV4 in …

[HTML][HTML] TRP channels as molecular targets to relieve cancer pain

M Duitama, Y Moreno, SP Santander, Z Casas… - Biomolecules, 2021 - mdpi.com
Transient receptor potential (TRP) channels are critical receptors in the transduction of
nociceptive stimuli. The microenvironment of diverse types of cancer releases substances …

[HTML][HTML] Activation of PTEN by inhibition of TRPV4 suppresses colon cancer development

X Liu, P Zhang, C Xie, KWY Sham, SSM Ng… - Cell death & …, 2019 - nature.com
Transient receptor potential vanilloid type 4 (TRPV4) is a Ca2+-permeable cation channel
that is known to be an osmosensor and thermosensor. Currently, limited evidence shows …

Expression and functionality of TRPV1 in breast cancer cells

LV Weber, K Al-Refae, G Wölk, G Bonatz… - … Cancer: Targets and …, 2016 - Taylor & Francis
Transient receptor potential (TRP) channels contribute to the regulation of intracellular
calcium, which can promote cancer hallmarks in cases of dysregulation of gene transcription …

TRPV channels in tumor growth and progression

G Santoni, V Farfariello, C Amantini - Transient Receptor Potential …, 2011 - Springer
Transient receptor potential (TRP) channels affect several physiological and pathological
processes. In particular, TRP channels have been recently involved in the triggering of …