[HTML][HTML] Gold nanoparticles induced size dependent cytotoxicity on human alveolar adenocarcinoma cells by inhibiting the ubiquitin proteasome system

B Ibrahim, TH Akere, S Chakraborty, E Valsami-Jones… - Pharmaceutics, 2023 - mdpi.com
Gold nanoparticles (AuNPs) are widely used in biomedicine due to their remarkable
therapeutic applications. However, little is known about their cytotoxic effects on the ubiquitin …

Functionalized gold nanoparticles suppress the proliferation of human lung alveolar adenocarcinoma cells by deubiquitinating enzymes inhibition

B Ibrahim, TH Akere, S Chakraborty… - ACS …, 2023 - ACS Publications
Functionalized gold nanoparticles (AuNPs) are widely used in therapeutic applications, but
little is known regarding the impact of their surface functionalization in the process of toxicity …

Size-and cell type-dependent cellular uptake, cytotoxicity and in vivo distribution of gold nanoparticles

Q Xia, J Huang, Q Feng, X Chen, X Liu… - International journal …, 2019 - Taylor & Francis
Background Gold nanoparticles (AuNPs) have shown great promise in biomedical
applications. However, the interaction of AuNPs with biological systems, its underlying …

In vitro toxicity of serum protein-adsorbed citrate-reduced gold nanoparticles in human lung adenocarcinoma cells

SY Choi, S Jeong, SH Jang, J Park, JH Park, KS Ock… - Toxicology in vitro, 2012 - Elsevier
We examined the cytotoxicity effect of the serum protein coated gold nanoparticles (AuNPs)
in the A549 cells. Negatively charged AuNPs were prepared by chemical reduction using …

Biogenic gold nanoparticles induce cell cycle arrest through oxidative stress and sensitize mitochondrial membranes in A549 lung cancer cells

V Ramalingam, S Revathidevi, T Shanmuganayagam… - RSC …, 2016 - pubs.rsc.org
The present study aims to find a facile, green and more yielding approach for the synthesis
of high stability gold nanoparticles (AuNPs) with a monodispersed nature using an aqueous …

Differential cytotoxic effects of gold nanoparticles in different mammalian cell lines

PJ Chueh, RY Liang, YH Lee, ZM Zeng… - Journal of hazardous …, 2014 - Elsevier
Gold nanoparticles (AuNPs) possess unique properties that have been exploited in several
medical applications. However, a more comprehensive understanding of the environmental …

[HTML][HTML] Gold nanoparticles induce cytotoxicity in the alveolar type-II cell lines A549 and NCIH441

C Uboldi, D Bonacchi, G Lorenzi, MI Hermanns… - Particle and fibre …, 2009 - Springer
Background During the last years engineered nanoparticles (NPs) have been extensively
used in different technologies and consequently many questions have arisen about the risk …

Gold nanoparticle induces mitochondria-mediated apoptosis and cell cycle arrest in nonsmall cell lung cancer cells

V Ramalingam, S Revathidevi, TS Shanmuganayagam… - Gold Bulletin, 2017 - Springer
The present study reports the chemical synthesis of gold nanoparticles (AuNPs) using
sodium borohydride as a reducing and capping agent. The various temperatures and time …

[HTML][HTML] A proteomic approach to investigate AuNPs effects in Balb/3T3 cells

S Gioria, H Chassaigne, D Carpi, A Parracino… - Toxicology letters, 2014 - Elsevier
Although gold nanoparticles (AuNPs) are currently used in several industrial products and
biomedical applications, information about their biological effects is very limited. Thus, it is …

Gold nanoparticles induced apoptosis via oxidative stress and mitochondrial dysfunctions in MCF‐7 breast cancer cells

E Kowsalya, K MosaChristas… - Applied …, 2021 - Wiley Online Library
Green synthesis of functionalized gold nanoparticles has been considered to be more
biocompatible and has gained much attention in recent years. The eco‐friendly synthesis …