Mesenchymal stem cell‐based treatments for stroke, neural trauma, and heat stroke

YCY Hsuan, CH Lin, CP Chang, MT Lin - Brain and behavior, 2016 - Wiley Online Library
Background Mesenchymal stem cell (MSC) transplantation has been reported to improve
neurological function following neural injury. Many physiological and molecular …

Ischemic brain stroke and mesenchymal stem cells: An overview of molecular mechanisms and therapeutic potential

Y Jingli, W Jing, Y Saeed - Stem Cells International, 2022 - Wiley Online Library
Ischemic brain injury is associated with a high rate of mortality and disability with no effective
therapeutic strategy. Recently, a growing number of studies are focusing on mesenchymal …

Mesenchymal stem cells: therapeutic outlook for stroke

O Honmou, R Onodera, M Sasaki, SG Waxman… - Trends in molecular …, 2012 - cell.com
Adult bone marrow-derived mesenchymal stem cells (MSCs) display a spectrum of
functional properties. Transplantation of these cells improves clinical outcome in models of …

[HTML][HTML] Mesenchymal stromal cells in ischemic brain injury

B Brooks, D Ebedes, A Usmani, JV Gonzales-Portillo… - Cells, 2022 - mdpi.com
Ischemic brain injury represents a major cause of death worldwide with limited treatment
options with a narrow therapeutic window. Accordingly, novel treatments that extend the …

[HTML][HTML] The potential of mesenchymal stem cells for neural repair

RH Miller, L Bai, DP Lennon… - Discovery …, 2010 - discoverymedicine.com
Developing effective therapies for serious neurological insults remains a major challenge for
biomedical research. Despite intense efforts, the ability to promote functional recovery after …

Bone marrow-derived mesenchymal stem cells for the treatment of ischemic stroke

P Dharmasaroja - Journal of Clinical Neuroscience, 2009 - Elsevier
Bone marrow-derived mesenchymal stem cells (MSCs) have great potential as therapeutic
agents in stroke management, since they are easily accessible and can be rapidly …

Transplanting mesenchymal stem cells for treatment of ischemic stroke

F Wang, H Tang, J Zhu, JH Zhang - Cell transplantation, 2018 - journals.sagepub.com
Stroke is a major disease that leads to high mortality and morbidity. Given the ageing
population and the potential risk factors, the prevalence of stroke and socioeconomic burden …

[HTML][HTML] Mesenchymal stem cells in the treatment of traumatic brain injury

A Hasan, G Deeb, R Rahal, K Atwi, S Mondello… - Frontiers in …, 2017 - frontiersin.org
Traumatic brain injury (TBI) is characterized by a disruption in the normal function of the
brain due to an injury following a trauma, which can potentially cause severe physical …

Mesenchymal stem cell therapy for the treatment of traumatic brain injury: progress and prospects

M Das, K Mayilsamy, SS Mohapatra… - Reviews in the …, 2019 - degruyter.com
Traumatic brain injury (TBI) is a major cause of injury-related mortality and morbidity in the
USA and around the world. The survivors may suffer from cognitive and memory deficits …

Mesenchymal stem cell therapy modulates the inflammatory response in experimental traumatic brain injury

LT Galindo, TRM Filippo, P Semedo… - Neurology research …, 2011 - Wiley Online Library
Therapy with mesenchymal stem cells (MSCs) has showed to be promising due to its
immunomodulatory function. Traumatic brain injury (TBI) triggers immune response and …