Glomerulopathies with nephrotic syndrome that are resistant to therapy often progress to
end-stage chronic kidney disease (CKD) and require timely and accurate diagnosis …

Purpose Since human urine is the most readily available biofluid whose proteome changes
in response to disease, it is a logical sample for identifying protein biomarkers for kidney …

Biomarkers have the potential to greatly facilitate diagnosis and treatment of patients with
various forms of kidney disease. State-of-the-art mass spectrometry-based methods possess …

Introduction: Kidney dysfunction poses a high burden on patients and health care systems.
Early detection and accurate prediction of kidney disease progression remains a major …

The diagnosis and treatment of glomerular diseases are now based primarily on clinical
manifestations, urinary protein excretion levels and renal histology. Renal biopsy is an …

With the technological advances of mass spectrometry (MS)-based platforms, clinical
proteomics is one of the most rapidly growing areas in biomedical research. Urine …

Kidney injury is a complication frequently encountered in hospitalized patients. Early
detection of kidney injury prior to loss of renal function is an unmet clinical need that should …

Urinary proteomics has become one of the most attractive topics in disease biomarker
discovery. MS‐based proteomic analysis has advanced continuously and emerged as a …

Serum or plasma is frequently utilized in biomedical research; however, its application is
impeded by the requirement for invasive sample collection. The non-invasive nature of urine …

Urine is a biological material that can be easily obtained in the clinic. The identification of
proteins excreted in urine provides useful biological information about the kidney as well as …