Targeting cancer cells with biotin–dendrimer conjugates

W Yang, Y Cheng, T Xu, X Wang, L Wen - European journal of medicinal …, 2009 - Elsevier
Star-burst dendrimers represent a superior carrier platform for targeted drug delivery.
Partially acetylated generation 5 (G5) polyamidoamine (PAMAM) dendrimer was conjugated …

Surface modified dendrimers: synthesis and characterization for cancer targeted drug delivery

A Sharma, SP Gautam, AK Gupta - Bioorganic & medicinal chemistry, 2011 - Elsevier
Dendrimers represents a highly branched three-dimensional structure that provides a high
degree of surface functionality and versatility. PAMAM dendrimers are used as well-defined …

Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives

Y Cheng, L Zhao, Y Li, T Xu - Chemical Society Reviews, 2011 - pubs.rsc.org
In the past decade, nanomedicine with its promise of improved therapy and diagnostics has
revolutionized conventional health care and medical technology. Dendrimers and dendrimer …

Recent advances in dendrimer-based nanovectors for tumor-targeted drug and gene delivery

P Kesharwani, AK Iyer - Drug discovery today, 2015 - Elsevier
Highlights•Dendrimers are nanovectors with well-defined architecture and tunable surface
characteristics.•Dendrimers can take advantage of passive and active tumor targeting for …

Surface functionalized dendrimers as controlled-release delivery nanosystems for tumor targeting

M Ghaffari, G Dehghan, F Abedi-Gaballu… - European Journal of …, 2018 - Elsevier
Dendrimers are nano-sized and three-dimensional macromolecules with well-defined
globular architecture and are widely used in various aspects such as drug and gene delivery …

RGD peptide-modified multifunctional dendrimer platform for drug encapsulation and targeted inhibition of cancer cells

X He, CS Alves, N Oliveira, J Rodrigues, J Zhu… - Colloids and Surfaces B …, 2015 - Elsevier
Abstract Development of multifunctional nanoscale drug-delivery systems for targeted
cancer therapy still remains a great challenge. Here, we report the synthesis of cyclic …

Dendrimer nanoarchitectures for cancer diagnosis and anticancer drug delivery

AK Sharma, A Gothwal, P Kesharwani, H Alsaab… - Drug Discovery …, 2017 - Elsevier
Highlights•Dendrimers are efficient nanocarriers having biomedical and diagnostic
application potentials.•Dendrimers can be efficiently encapsulated with drugs by host–guest …

Preparation, cellular transport, and activity of polyamidoamine-based dendritic nanodevices with a high drug payload

P Kolhe, J Khandare, O Pillai, S Kannan, M Lieh-Lai… - Biomaterials, 2006 - Elsevier
Dendrimers are emerging as a relatively new class of polymeric biomaterials with
applications in drug delivery, and imaging. Achieving a high drug payload in dendrimers …

Design of riboflavin-presenting PAMAM dendrimers as a new nanoplatform for cancer-targeted delivery

TP Thomas, SK Choi, MH Li, A Kotlyar… - Bioorganic & medicinal …, 2010 - Elsevier
This communication describes the synthesis and in vitro biological evaluation of novel
generation 5 PAMAM dendrimers conjugated with riboflavin as a targeting ligand. Cell …

Peptide dendrimer–doxorubicin conjugate‐based nanoparticles as an enzyme‐responsive drug delivery system for cancer therapy

C Zhang, D Pan, K Luo, W She, C Guo… - Advanced …, 2014 - Wiley Online Library
Peptide dendrimers have shown promise as an attractive platform for drug delivery. In this
study, mPEGylated peptide dendrimer–doxorubicin (dendrimer–DOX) conjugate‐based …