[HTML] nih.gov

[HTML][HTML] Antitumor efficacy of 90Y-NM600 targeted radionuclide therapy and PD-1 blockade is limited by regulatory T cells in murine prostate tumors

HK Potluri, CA Ferreira, J Grudzinski… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background Systemic radiation treatments that preferentially irradiate cancer cells over
normal tissue, known as targeted radionuclide therapy (TRT), have shown significant …
被引用次数：13 相关文章 所有 6 个版本
[HTML] nih.gov

[HTML][HTML] Myeloid-derived suppressor cells attenuate the antitumor efficacy of radiopharmaceutical therapy using 90Y-NM600 in combination with androgen deprivation …

A Muralidhar, R Hernandez, ZS Morris… - … for Immunotherapy of …, 2024 - ncbi.nlm.nih.gov
Methods 6-week-old male FVB mice were implanted subcutaneously with Myc-CaP tumor
cells and given a single intravenous injection of 90 Y-NM600, in combination with ADT …
被引用次数：1 相关文章 所有 5 个版本
[PDF] springer.com

Combination immunotherapy and radiotherapy causes an abscopal treatment response in a mouse model of castration resistant prostate cancer

SO Dudzinski, BD Cameron, J Wang… - … for immunotherapy of …, 2019 - Springer
Background Prostate cancer is poorly responsive to immune checkpoint inhibition, yet a
combination with radiotherapy may enhance the immune response. In this study, we …
被引用次数：78 相关文章 所有 14 个版本
[PDF] nature.com

Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model

Y Philippou, HT Sjoberg, E Murphy, S Alyacoubi… - British journal of …, 2020 - nature.com
Background Radiotherapy enhances innate and adaptive anti-tumour immunity. It is unclear
whether this effect may be harnessed by combining immunotherapy with radiotherapy …
被引用次数：65 相关文章 所有 10 个版本
[PDF] mdpi.com

Targeted Radiation and Immune Therapies—Advances and Opportunities for the Treatment of Prostate Cancer

A Muralidhar, HK Potluri, T Jaiswal, DG McNeel - Pharmaceutics, 2023 - mdpi.com
Prostate cancer is the most diagnosed malignancy in men in the United States and the
second leading cause of cancer-related death. For localized disease, radiation therapy is a …
被引用次数：5 相关文章 所有 6 个版本
[PDF] tandfonline.com

Reprogramming the immunosuppressive tumor microenvironment results in successful clearance of tumors resistant to radiation therapy and anti-PD-1/PD-L1

D Mukherjee, E Romano, R Walshaw, LAH Zeef… - …, 2023 - Taylor & Francis
Despite breakthroughs in immune checkpoint inhibitors (ICI), the majority of tumors,
including those poorly infiltrated by CD8+ T cells or heavily infiltrated by immunosuppressive …
被引用次数：4 相关文章 所有 10 个版本

High-dose per fraction radiotherapy induces both antitumor immunity and immunosuppressive responses in prostate tumors

L Lin, N Kane, N Kobayashi, EA Kono… - Clinical Cancer …, 2021 - AACR
Purpose: The use of high-dose per fraction radiotherapy delivered as stereotactic body
radiotherapy is a standard of care for prostate cancer. It is hypothesized that high-dose …
被引用次数：52 相关文章 所有 3 个版本
[HTML] nih.gov

Radiotherapy augments the immune response to prostate cancer in a time‐dependent manner

TJ Harris, EL Hipkiss, S Borzillary, S Wada… - The …, 2008 - Wiley Online Library
BACKGROUND Cancer immunotherapy refers to an array of strategies intended to treat
progressive tumors by augmenting a patient's anti‐tumor immune response. As …
被引用次数：99 相关文章 所有 9 个版本
[PDF] aacrjournals.org

Targeted radionuclide therapy with low and high-dose lutetium-177–labeled single domain antibodies induces distinct immune signatures in a mouse melanoma …

T Ertveldt, L De Beck, K De Ridder, H Locy… - Molecular Cancer …, 2022 - AACR
Targeted radionuclide therapy (TRT) using probes labeled with Lutetium-177 (177Lu)
represents a new and growing type of cancer therapy. We studied immunologic changes in …
被引用次数：7 相关文章 所有 9 个版本
[HTML] nih.gov

Combined treatment effects of radiation and immunotherapy: studies in an autochthonous prostate cancer model

S Wada, TJ Harris, E Tryggestad, K Yoshimura… - International Journal of …, 2013 - Elsevier
Purpose To optimize the combination of ionizing radiation and cellular immunotherapy using
a preclinical autochthonous model of prostate cancer. Methods and Materials Transgenic …
被引用次数：23 相关文章 所有 12 个版本