Obesity is a metabolic state generated by the expansion of adipose tissue. Adipose tissue
expansion depends on the interplay between hyperplasia and hypertrophy, and is mainly …

Bardet-Biedl syndrome (BBS) is an autosomal recessive disorder associated with marked
obesity. Research in rare forms of obesity has identified genes with significant roles in …

Bardet–Biedl Syndrome (BBS) is a rare human hereditary disorder associated with several
features including obesity, retinopathy, renal defects, polydactyly, learning disabilities and …

Bardet-Biedl syndrome (BBS) is a highly pleiotropic autosomal recessive disorder
associated with a wide range of phenotypes including obesity. However, the underlying …

Bardet-Biedl syndrome (BBS) is a heterogeneous genetic disorder characterized by many
features, including obesity and cardiovascular disease. We previously developed knockout …

Bardet-Biedl syndrome (BBS) is a rare developmental disorder with the cardinal features of
abdominal obesity, retinopathy, polydactyly, cognitive impairment, renal and cardiac …

INTRODUCTION: Obesity is a consistent presenting feature of the Bardet–Biedl syndrome
(BBS), a hereditary disorder caused by a single gene defect. This contrasts sharply with …

Summary Background Bardet‐Biedl syndrome (BBS) is a rare genetic disorder that severely
inhibits primary cilia function. BBS is typified by obesity in adulthood, but pediatric weight …

Studying ciliopathies, like the Bardet-Biedl syndrome (BBS), allow the identification of
signaling pathways potentially involved in common diseases, sharing phenotypic features …

Rare genetic obesity disorders are characterized by mutations of genes strongly involved in
the central or peripheral regulation of energy balance. These mutations are effective in …