Animal models of metabolic syndrome: a review

SK Wong, KY Chin, FH Suhaimi, A Fairus… - Nutrition & …, 2016 - Springer
Metabolic syndrome (MetS) consists of several medical conditions that collectively predict
the risk for cardiovascular disease better than the sum of individual conditions. The risk of …

Mouse models of the metabolic syndrome

AJ Kennedy, KLJ Ellacott, VL King… - Disease models & …, 2010 - journals.biologists.com
The metabolic syndrome (MetS) is characterized by obesity concomitant with other
metabolic abnormalities such as hypertriglyceridemia, reduced high-density lipoprotein …

Biochemical and nutritional overview of diet-induced metabolic syndrome models in rats: what is the best choice?

E Rodríguez-Correa, I González-Pérez… - Nutrition & …, 2020 - nature.com
Metabolic syndrome (MS) is a condition that includes obesity, insulin resistance,
dyslipidemias among other, abnormalities that favors type 2 Diabetes Mellitus (T2DM) and …

Rodent models for metabolic syndrome research

SK Panchal, L Brown - BioMed Research International, 2011 - Wiley Online Library
Rodents are widely used to mimic human diseases to improve understanding of the causes
and progression of disease symptoms and to test potential therapeutic interventions …

Diet‐induced rodent models of obesity‐related metabolic disorders—a guide to a translational perspective

I Preguiça, A Alves, S Nunes, R Fernandes… - Obesity …, 2020 - Wiley Online Library
Diet is a critical element determining human health and diseases, and unbalanced food
habits are major risk factors for the development of obesity and related metabolic disorders …

C57BL/6J and A/J mice fed a high‐fat diet delineate components of metabolic syndrome

C Gallou‐Kabani, A Vigé, MS Gross, JP Rabès… - …, 2007 - Wiley Online Library
Objective: The aim of this study was to assess the suitability of A/J and C57BL/6J mice of
both sexes as models of some components of the human metabolic syndrome (MetS) under …

A mouse model of diet-induced obesity resembling most features of human metabolic syndrome

MC Della Vedova, MD Muñoz… - Nutrition and …, 2016 - journals.sagepub.com
Increased chicken-derived fat and fructose consumption in the human diet is paralleled by
an increasing prevalence of obesity and metabolic syndrome (MS). Herein, we aimed at …

Mice long-term high-fat diet feeding recapitulates human cardiovascular alterations: an animal model to study the early phases of diabetic cardiomyopathy

SD Calligaris, M Lecanda, F Solis, M Ezquer… - PloS one, 2013 - journals.plos.org
Background/Aim Hypercaloric diet ingestion and sedentary lifestyle result in obesity.
Metabolic syndrome is a cluster of clinical features secondary to obesity, considered as a …

New advances in metabolic syndrome, from prevention to treatment: the role of diet and food

D Ambroselli, F Masciulli, E Romano, G Catanzaro… - Nutrients, 2023 - mdpi.com
The definition of metabolic syndrome (MetS) has undergone several changes over the years
due to the difficulty in establishing universal criteria for it. Underlying the disorders related to …

Small animal models of cardiovascular disease: tools for the study of the roles of metabolic syndrome, dyslipidemia, and atherosclerosis

JC Russell, SD Proctor - Cardiovascular pathology, 2006 - Elsevier
INTRODUCTION: Cardiovascular disease, the leading cause of death in much of the
modern world, is the common symptomatic end stage of a number of distinct diseases and …