Spices and herbs often contain active phenolic substances endowed with potent
antioxidative properties. We had previously shown that curcumin, the yellow pigment in …

Curcumin has been traditionally used in China and India for food and medicinal purposes. It
has been shown to possess potent antioxidative activity both in vitro and in vivo. In the …

Scope We have studied if curcumin can protect glial cells under an oxidative stress and
inflammatory environment, which is known to be deleterious in neurodegeneration. Methods …

The global burden of neurodegenerative disorders has increased substantially over the past
2 decades due to rising rates of population aging. Although neurodegenerative disorders …

Curcumin is a bifunctional antioxidant derived from Curcuma longa. This study identifies
curcumin as a neuroprotectant against hemin‐induced damage in primary cultures of …

Parkinson's disease (PD) is an age‑related complex neurodegenerative disease that
affects≤ 80% of dopaminergic neurons in the substantia nigra pars compacta (SNpc). It has …

Curcumin is a polyphenol compound extracted from the rhizome of Curcuma longa Linn
(family Zingiberaceae) commonly used as a spice to color and flavor food. Several …

Curcumin is a natural polyphenol component of Curcuma longa Linn, which is currently
considered one of the most effective nutritional antioxidants for counteracting free radical …

In the CNS, the heme oxygenase (HO) system has been reported to be active and to operate
as a fundamental defensive mechanism for neurons exposed to an oxidant challenge. We …

Free radicals play a main pathogenic role in several human diseases such as
neurodegenerative disorders, diabetes, and cancer. Although there has been progress in …